stiripentol

Known as: 1-(1,3-benzodioxol-5-yl)-4,4- dimethyl-1-penten-3-ol 
 
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
Neuronal excitation is regulated by energy metabolism, and drug-resistant epilepsy can be suppressed by special diets. Here, we… (More)
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2014
2014
Dravet syndrome (DS) is a rare, severe childhood epilepsy syndrome that imposes a substantial burden on patients and their… (More)
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Highly Cited
2013
Highly Cited
2013
Dravet syndrome is a catastrophic pediatric epilepsy with severe intellectual disability, impaired social development and… (More)
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2012
2012
A series of stiripentol (STP) analogues namely, 2-[(1E)-1-(1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ylidene]-N-(aryl/H… (More)
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2009
2009
Stiripentol (STP) has been used as co-therapy for treatment of epilepsy for many years. Its mechanism of action has long been… (More)
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2006
2006
A metabolic interaction between stiripentol (STP), an anticonvulsant agent that inhibits the activity of several cytochromes P450… (More)
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1997
1997
OBJECTIVE The spectrum of cytochrome P450 inhibition of stiripentol, a new anticonvulsant, was characterized in vitro and in vivo… (More)
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1986
1986
The metabolism of stiripentol (I), a new antiepileptic drug, was studied in healthy human subjects. Following a single 1200-mg… (More)
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1984
1984
4,4-Dimethyl-1-[3,4-(methylenedioxy)-phenyl]-1-penten-3-ol (stiripentol), selected from a series of alpha-ethylene alcohols… (More)
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1983
1983
The pharmacokinetics and metabolism of stiripentol, a new antiepileptic drug, were investigated in normal male subjects after… (More)
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