steganacin
National Institutes of Health
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The asymmetric synthesis of novel axially chiral biaryl compounds 5 a-f containing a seven- or eight-membered heterocyclic medium…
The precise segregation of replicated chromosomes to daughter cells during mitosis depends on the formation of a bipolar spindle…
The cytotoxic activities of optically pure and racemic steganacin congeners and analogues against KB cells in culture and the…
New steganacin analogs with definite absolute configurations, (-)-picro- and (-)-epipicrosteganol, were synthesized by…
A highly efficient synthesis of the antitumor steganin lignan steganacin (1) was accomplished. Bromination of stegane (7) with N…
The cross-resistances of several mutants of Chinese hamster ovary cells which have been obtained after one and two selection…
A new series of 23 synthetic analogues of the naturally occurring antitumor lignan steganacin was tested for the inhibition of…