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Molecular signatures and phylogenomic analysis of the genus Burkholderia: proposal for division of this genus into the emended genus Burkholderia containing pathogenic organisms and a new genus
The genus Burkholderia contains large number of diverse species which include many clinically important organisms, phytopathogens, as well as environmental species. However, currently, there is aExpand
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Protein Phylogenies and Signature Sequences: A Reappraisal of Evolutionary Relationships among Archaebacteria, Eubacteria, and Eukaryotes
  • R. Gupta
  • Biology, Medicine
  • Microbiology and Molecular Biology Reviews
  • 1 December 1998
SUMMARY The presence of shared conserved insertion or deletions (indels) in protein sequences is a special type of signature sequence that shows considerable promise for phylogenetic inference. AnExpand
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Phylogenetic analysis of the 90 kD heat shock family of protein sequences and an examination of the relationship among animals, plants, and fungi species.
  • R. Gupta
  • Biology, Medicine
  • Molecular biology and evolution
  • 1 November 1995
The heat shock protein (Hsp) sequences, because of their ubiquity and high degree of conservation, provide useful models for phylogenetic analysis. In this paper I have carried out a global alignmentExpand
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Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera
The genus Mycobacterium contains 188 species including several major human pathogens as well as numerous other environmental species. We report here comprehensive phylogenomics and comparativeExpand
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The phylogeny of proteobacteria: relationships to other eubacterial phyla and eukaryotes.
  • R. Gupta
  • Biology, Medicine
  • FEMS microbiology reviews
  • 1 October 2000
The evolutionary relationships of proteobacteria, which comprise the largest and phenotypically most diverse division among prokaryotes, are examined based on the analyses of available molecularExpand
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Diversification of  T Cell Responses to Carboxy-terminal Determinants within the 65-kD Heat-shock Protein Is Involved in Regulation of Autoimmune Arthritis
The T cell response to the 65-kD mycobacterial heat-shock protein (Bhsp65) has been implicated in the pathogenesis of autoimmune arthritis. Adjuvant arthritis (AA) induced in the Lewis rat (RT-1l) byExpand
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Phylogenetic Framework and Molecular Signatures for the Main Clades of the Phylum Actinobacteria
SUMMARY The phylum Actinobacteria harbors many important human pathogens and also provides one of the richest sources of natural products, including numerous antibiotics and other compounds ofExpand
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Phylogenomics and signature proteins for the alpha Proteobacteria and its main groups
BackgroundAlpha proteobacteria are one of the largest and most extensively studied groups within bacteria. However, for these bacteria as a whole and for all of its major subgroups (viz. Rhizobiales,Expand
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Signature proteins that are distinctive characteristics of Actinobacteria and their subgroups
The Actinobacteria constitute one of the main phyla of Bacteria. Presently, no morphological and very few molecular characteristics are known which can distinguish species of this highly diverseExpand
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Signature sequences in diverse proteins provide evidence for the late divergence of the Order Aquificales.
  • E. Griffiths, R. Gupta
  • Biology, Medicine
  • International microbiology : the official journal…
  • 1 March 2004
The Aquificales species are presently believed to be the earliest branching lineage within Bacteria. However, the branching order of this group in different phylogenetic trees is highly variable andExpand
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