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4-Butyrolactone

Known as: Furanone, tetrahydro-2-, 4-Hydroxybutyric Acid Lactone, gamma-Butyrolactone 
One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (44)

30(S)-hydroxybullatacin4-acetylantroquinonol B4-deoxyannomontacin5-bromomethylene-2(5H)-furanone
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

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Review
2009
Review
2009
Microbial quorum sensing: a tool or a target for antimicrobial therapy?
Inter‐cell communication aided by released chemical signals when cell density reaches a critical concentration has been… 
Highly Cited
2007
Highly Cited
2007
Evolution of gamma-butyrolactone synthases and receptors in Streptomyces.
The gamma-butyrolactone regulatory system triggers secondary metabolism and/or morphological development in the Gram-positive… 
Highly Cited
2000
Highly Cited
2000
Bovine oocyte and embryo development following meiotic inhibition with butyrolactone I
In this study we have shown that butyrolactone I (BL‐I), a potent inhibitor of cyclin‐dependent kinases, inhibits meiotic… 
Highly Cited
1995
Highly Cited
1995
Evidence for cdk5 as a major activity phosphorylating tau protein in porcine brain extract.
The major kinase capable of phosphorylating tau in a porcine brain extract was suggested to be a brain cdc2-like kinase, called… 
Review
1994
Review
1994
A‐factor as a microbial hormone that controls cellular differentiation and secondary metabolism in Streptomyces griseus
A‐factor, containing a γ‐butyrolactone in its structure, is an autoregulatory factor or a‘microbiai hormone’controlling secondary… 
Highly Cited
1989
Highly Cited
1989
The popliteal lymph node assay in mice to screen for the immune disregulating potential of chemicals--a preliminary study.
Highly Cited
1982
Highly Cited
1982
Ventral root depolarization and spinal reflex augmentation by a TRH analog in rat spinal cord
Highly Cited
1981
Highly Cited
1981
Studies on mutagenic constituents of apple brandy and various alcoholic beverages collected in western France, a high incidence area for oesophageal cancer.
Highly Cited
1977
Highly Cited
1977
EFFECTS OF γ‐BUTYROLACTONE ON LOCAL CEREBRAL GLUCOSE UTILIZATION IN THE RAT
Abstract— The effects of graded doses of γ‐butyrolactone on the rates of glucose utilization in 29 structural components of the… 
Highly Cited
1972
Highly Cited
1972
Effect of gamma-hydroxybutyrate on dopamine and dopamine metabolites in the rat striatum.
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