spirogermanium

Known as: 2-Aza-8-germaspiro[4.5]decane-2-propanamine, 8, 8-diethyl-N,N-dimethyl-, Dihydrochloride, Spiro-32, 2-[3-(Dimethyl-amino)propyl]-8,8-diethyl-2-aza-8-germaspiro[4,5]decane 
A synthetic organometallic compound containing the element germanium with possible antineoplastic activity. Spirogermanium exhibits significant… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2018
0204019652018

Papers overview

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Review
2015
Review
2015
BACKGROUND Human pepsinogens are considered promising serological biomarkers for the screening of atrophic gastritis (AG) and… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND The pain and autonomic symptoms of cluster headache (CH) result from activation of the trigeminal parasympathetic… (More)
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2011
2011
Oceanic subtropical gyres are considered biological deserts because of the extremely low availability of nutrients and thus… (More)
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2009
2009
BACKGROUND We report preliminary results of a novel acute treatment for intractable migraine. The sphenopalatine ganglion (SPG… (More)
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2009
2009
Beta-site APP cleaving enzyme 1 (BACE1) is a transmembrane aspartyl protease with a lumenal active site that sheds the… (More)
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Highly Cited
2000
Highly Cited
2000
Pelizaeus-Merzbacher disease (PMD) and spastic paraplegia type 2 (SPG2) are X-linked developmental defects of myelin formation… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND We have shown previously that norepinephrine (NE) uptake activity is reduced in the failing right ventricle of animals… (More)
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Highly Cited
1980
Highly Cited
1980
A modification of the SPG histofluorescence method for the visualization of monoamines in tissues using cryostat sections is… (More)
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1980
1980
Spirogermanium is a new azaspirane antitumor agent, with the metal germanium substituted for a one-carbon moiety in the ring… (More)
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Highly Cited
1976
Highly Cited
1976
A modified approach of the glyoxylic acid (GA) condensation reaction for the visualization of biogenic amines in tissue is… (More)
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