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Enhancement of cytokine production by macrophages stimulated with (1-->3)-beta-D-glucan, grifolan (GRN), isolated from Grifola frondosa.
TLDR
GRN is a novel macrophage activator which augments cytokine production without dependence on endotoxins, and was more effective than LPS used in this study.
Antitumor β-Glucan from the Cultured Fruit Body of Agaricus blazei
TLDR
Factors strongly suggest that a highly branched 1,3-beta-glucan segment forms the active center of the antitumor activity of A. blazei.
Contribution of CR3 to nitric oxide production from macrophages stimulated with high-dose of LPS.
TLDR
The results suggest that the CR3 molecule acts in a CD14-independent signaling pathway, and contributes to NO production by macrophages stimulated with high doses of LPS.
Immunomodulation by orally administered beta-glucan in mice.
TLDR
It is demonstrated that SSG can potentiate the immune response of mice following oral administration and significant inhibition of tumor growth was observed in syngeneic tumor systems when SSG was administered directly after tumor implantation.
Effect of SCG, 1,3-beta-D-glucan from Sparassis crispa on the hematopoietic response in cyclophosphamide induced leukopenic mice.
TLDR
The possibility that IL-6 might be a key cytokine for the enhanced hematopoietic response by SCG is suggested.
Effect of orally administered beta-glucan on macrophage function in mice.
TLDR
It is shown that SSG given by the oral route can activate peritoneal macrophages in mice and the durations of the activated state after completion of administration differed depending on the activity.
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