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spirapril

Known as: 1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid, 7-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, (8S-(7(R*(R*)),8R*))- 
A prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Spirapril is converted in the body to its… 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Specific features of the 24-h blood pressure (BP) pattern are linked to progressive injury of target tissues and risk of… 
Review
2011
Review
2011
Specific features of the 24 h-blood pressure (BP) pattern are linked to the progressive injury of target tissues and risk of… 
Highly Cited
1995
Highly Cited
1995
Administration of angiotensin-converting-enzyme (ACE) inhibitors reduce vascular proliferation following endothelial injury as… 
1993
1993
To test whether angiotensin-converting enzyme (ACE) inhibition may prevent myocardial damage and may affect coronary… 
Highly Cited
1992
Highly Cited
1992
Objective To investigate whether the compensatory rise in renin and plasma angiotensin 1 in response to repeated angiotensin… 
Highly Cited
1991
Highly Cited
1991
1. This study was undertaken to examine the possibility that the level of angiotensin‐converting enzyme (ACE) increases in… 
1989
1989
The synthesis of spirapril (5), spiraprilat (25), their RSS stereoisomers, and their glycyl (18b) and lysyl (36, 37) analogues is…