Skip to search formSkip to main contentSkip to account menu

spinorphin

Known as: L-Threonine, N-(N-(1-(N-(N-(N-L-leucyl-L-valyl)-L-valyl)-L-tyrosyl)-L-prolyl)-L-tryptophyl)-, Leu-Val-Val-Tyr-Pro-Trp-Thr, leucyl--valyl-valyl-tyrosyl-prolyl-tryptophyl-threonine 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Oligopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Enkephalinase inhibitors: potential agents for the management of pain.
Management of acute and chronic pain has always been a key area of clinical research. Enkephalinase inhibitors (EIs) seem to be… 
2007
2007
Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist.
Spinorphin, an endogenous antinociceptive peptide (LVVYPWT), showed potent and non-competitive antagonism at the ATP-activated… 
Review
2002
Review
2002
Spinorphin as an endogenous inhibitor of enkephalin-degrading enzymes: roles in pain and inflammation.
It is possible that enkephalins are involved in the pain-modulating mechanism in the spinal cord. Enkephalins, however, are short… 
2001
2001
The Endogenous Opioid Spinorphin Blocks fMet-Leu-Phe-Induced Neutrophil Chemotaxis by Acting as a Specific Antagonist at the N-Formylpeptide Receptor Subtype FPR
Spinorphin is an endogenous heptapeptide (leucylvalylvalyltyrosylprolyltryptophylthreonine), first isolated from bovine spinal… 
2001
2001
Spinorphin, an endogenous inhibitor of enkephalin-degrading enzymes, potentiates leu-enkephalin-induced anti-allodynic and antinociceptive effects in mice.
Spinorphin (LVVYPWT) has been isolated from the bovine spinal cord as an endogenous inhibitor of enkephalin-degrading enzymes. It… 
2000
2000
Characterization of tynorphin, a potent endogenous inhibitor of dipeptidyl peptidaseIII
2000
2000
Identification of dipeptidyl peptidase III in human neutrophils.
We have found activity of dipeptidyl peptidase (DPP) III, one of the most important enkephalin-degrading enzymes in the central… 
1997
1997
Investigation of inhibition angiotensin-converting enzyme (ACE) activity and opioid activity of two hemorphins, LVV-hemorphin-5 and VV-hemorphin-5, isolated from a defined peptic hydrolysate of…
Highly Cited
1993
Highly Cited
1993
Isolation and identification of an endogenous inhibitor of enkephalin-degrading enzymes from bovine spinal cord.
We isolated a potent inhibitor of enkephalin-degrading enzymes from bovine spinal cord and determined its amino-acid sequence and… 
1993
1993
[Study of a new endogenous inhibitor of enkephalin-degrading enzymes; pharmacological function and metabolism of spinorphin].
Spinorphin, a potent inhibitor of enkephalin degrading enzyme isolated from the bovine spinal cord, produces a dose-related… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)