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spindle assembly checkpoint

Known as: Spindle Assembly Checkpoints, SAC, Checkpoint, Spindle Assembly 
A cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the… Expand
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

M Phase Cell Cycle Checkpoints

Narrower (2)

meiotic spindle assembly checkpointmitotic spindle assembly checkpoint
spindle checkpoint activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
A single center experience
This study aimed to compare clinical results, symptom relief, quality of life and patient satisfaction after the 2 most common… Expand
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Review
2018
Review
2018
International consensus (ICON) on treatment of Ménière's disease.
OBJECTIVE To present the international consensus for recommendations for Ménière's disease (MD) treatment. METHODS Based on a… Expand
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Review
2018
Review
2018
Segregating Chromosomes in the Mammalian Oocyte
Chromosome segregation errors in human oocytes lead to aneuploid embryos that cause infertility and birth defects. Here we… Expand
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Review
2018
Review
2018
What Exactly is Meant by “Loss of Domain” for Ventral Hernia? Systematic Review of Definitions
Large ventral hernias are a significant surgical challenge. “Loss of domain” (LOD) expresses the relationship between hernia and… Expand
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Highly Cited
2003
Highly Cited
2003
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint
The proper segregation of sister chromatids in mitosis depends on bipolar attachment of all chromosomes to the mitotic spindle… Expand
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Highly Cited
2000
Highly Cited
2000
Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5
Monastrol, a cell-permeable small molecule inhibitor of the mitotic kinesin, Eg5, arrests cells in mitosis with monoastral… Expand
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Highly Cited
1999
Highly Cited
1999
Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995.
 
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Highly Cited
1996
Highly Cited
1996
Association of Spindle Assembly Checkpoint Component XMAD2 with Unattached Kinetochores
The spindle assembly checkpoint delays anaphase until all chromosomes are attached to a mitotic spindle. The mad (mitotic arrest… Expand
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Highly Cited
1996
Highly Cited
1996
[Gastric cancer].
  • H. Espejo
  • Revista de gastroenterologia del Peru : organo…
  • 1996
    • Corpus ID: 614241
The stomach is a sac-like organ located between the esophagus and small intestine. The stomach aids in digestion and stores food… Expand
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Highly Cited
1995
Highly Cited
1995
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
THE receptor tyrosine kinase Flk-1 (ref. 1) is believed to play a pivotal role in endothelial development. Expression of the Flk… Expand
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