Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 227,741,304 papers from all fields of science
Search
Sign In
Create Free Account
sphingomyelin phosphodiesterase activity
Known as:
sphingomyelin cholinephosphohydrolase activity
, sphingomyelinase activity
Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+). [EC:3.1.4.12, RHEA:19256]
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
3 relations
SPHINGOMYELINASE
acid sphingomyelinase
Narrower (1)
acid sphingomyelin phosphodiesterase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Molecular Mechanisms of Fenretinide‐Induced Apoptosis of Neuroblastoma Cells
P. Lovat
,
Marco Corazzari
,
B. Goranov
,
M. Piacentini
,
C. Redfern
Annals of the New York Academy of Sciences
2004
Corpus ID: 11560789
Abstract: Synthetic retinoids such as fenretinide [N‐(4‐hydroxyphenyl)retinamide] induce apoptosis of neuroblastoma cells, act…
Expand
Highly Cited
2003
Highly Cited
2003
Ceramide in rafts (detergent‐insoluble fraction) mediates cell death in neurotumor cell lines
J. Kilkus
,
R. Goswami
,
F. Testai
,
G. Dawson
Journal of Neuroscience Research
2003
Corpus ID: 29929358
Detergent‐resistant lipid microdomains (Rafts) were isolated from human oligodendroglioma (HOG), human neuroblastoma (LA‐N‐5…
Expand
2000
2000
Coenzyme Q protects cells against serum withdrawal-induced apoptosis by inhibition of ceramide release and caspase-3 activation.
D. M. Fernández-Ayala
,
Sergio F. Martín
,
+5 authors
Plácido Navas
Antioxidants and Redox Signaling
2000
Corpus ID: 2253976
Coenzyme Q10 (CoQ10) is a component of the antioxidant machinery that protects cell membranes from oxidative damage and decreases…
Expand
1997
1997
Myelin contains neutral sphingomyelinase activity that is stimulated by tumor necrosis factor‐α
G. Chakraborty
,
S. Ziemba
,
A. Drivas
,
R. Ledeen
Journal of Neuroscience Research
1997
Corpus ID: 7192104
Purified myelin from mouse brain was found to contain two forms of neutral sphingomyelinase, one Mg2+ dependent and the other Mg2…
Expand
Highly Cited
1995
Highly Cited
1995
Alkaline sphingomyelinase activity in rat gastrointestinal tract: distribution and characteristics.
R. Duan
,
L. Nyberg
,
A. Nilsson
Biochimica et Biophysica Acta
1995
Corpus ID: 25247503
Highly Cited
1991
Highly Cited
1991
Reversal of multidrug resistance by calcium channel blocker SR33557 without photoaffinity labeling of P-glycoprotein.
J. Jaffrezou
,
J. Herbert
,
T. Levade
,
M. Gau
,
P. Chatelain
,
G. Laurent
Journal of Biological Chemistry
1991
Corpus ID: 25443583
1990
1990
Very low levels of high density lipoprotein cholesterol in four sibs of a family with non-neuropathic Niemann-Pick disease and sea-blue histiocytosis.
M. Viana
,
R. Giugliani
,
+4 authors
A. Fensom
Journal of Medical Genetics
1990
Corpus ID: 37424923
Very low serum levels of high density lipoprotein cholesterol ranging from 8.6 to 13.9 mg/dl were detected in four out of 12 sibs…
Expand
1987
1987
Effects of gentamicin on sphingomyelinase activity in cultured human renal proximal tubular cells.
P. Ghosh
,
S. Chatterjee
Journal of Biological Chemistry
1987
Corpus ID: 43096340
Highly Cited
1982
Highly Cited
1982
In situ degradation of sphingomyelin by cultured normal fibroblasts and fibroblasts from patients with Niemann-Pick disease type A and C.
J. Mazière
,
C. Maziére
,
L. Mora
,
J. Routier
,
J. Polonovski
Biochemical and Biophysical Research…
1982
Corpus ID: 38612091
1967
1967
Phospholipases in arterial tissue. I. Sphingomyelin cholinephosphohydrolase activity in human, dog, guinea pig, rat and rabbit arteries.
D. Rachmilewitz
,
S. Eisenberg
,
Y. Stein
,
O. Stein
Biochimica et Biophysica Acta
1967
Corpus ID: 28828487
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE