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sphingomyelin phosphodiesterase activity

Known as: sphingomyelin cholinephosphohydrolase activity, sphingomyelinase activity 
Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+). [EC:3.1.4.12, RHEA:19256]
National Institutes of Health

Papers overview

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Review
2004
Review
2004
Abstract: Synthetic retinoids such as fenretinide [N‐(4‐hydroxyphenyl)retinamide] induce apoptosis of neuroblastoma cells, act… 
Highly Cited
2003
Highly Cited
2003
Detergent‐resistant lipid microdomains (Rafts) were isolated from human oligodendroglioma (HOG), human neuroblastoma (LA‐N‐5… 
2000
2000
Coenzyme Q10 (CoQ10) is a component of the antioxidant machinery that protects cell membranes from oxidative damage and decreases… 
1997
1997
Purified myelin from mouse brain was found to contain two forms of neutral sphingomyelinase, one Mg2+ dependent and the other Mg2… 
1990
1990
Very low serum levels of high density lipoprotein cholesterol ranging from 8.6 to 13.9 mg/dl were detected in four out of 12 sibs…