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spasmofen

Known as: Morphinan 3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5alpha,6alpha)-, hydrochloride, mixt. with (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol hydrochloride, 1-((3,4-dimethoxyphenyl)methyl)-6,7-dimethoxyisoquinoline hydrochloride, (S-(R*,S*))-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-1(3H)-isobenzofuranone hydrochloride and (7(S)-(1alpha,2beta,4beta,5alpha,7beta))-7-(3-hydroxy-1-oxo2-phenylpropoxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane 
 
National Institutes of Health

Papers overview

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2016
2016
Correction for the nonspecific binding (NSB) of drugs to liver microsomes is essential for the accurate measurement of the… Expand
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2014
2014
Background Renal colic is typically characterized by the sudden onset of severe pain radiating from the flank to the groin and… Expand
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2013
2013
Opioid narcotics are used for the treatment of moderate-to-severe pain and primarily exert their analgesic effects through… Expand
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2005
2005
Previous research has shown that compounds with mixed κ and μ activity may have utility for the treatment of cocaine abuse and… Expand
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2005
2005
Previous research has shown that compounds with mixed kappa and mu activity may have utility for the treatment of cocaine abuse… Expand
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2003
2003
A novel series of morphinans were synthesized, and their binding affinity at and functional selectivity for micro, delta, and… Expand
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Highly Cited
1998
Highly Cited
1998
Cytochromes mediating the biotransformation of dextromethorphan to dextrorphan and 3-methoxymorphinan, its principal metabolites… Expand
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1988
1988
The pain-reducing property of metoclopramide (Primperan) was compared with that of a narcotic combination drug (Spasmofen) in a… Expand
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1986
1986
The inhibition of prostaglandin synthesis by nonsteroidal anti-inflammatory drugs can alleviate the pain and inflammation… Expand
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1976
1976
The morphine-antagonistic properties of 5 novel compounds, (--)N-(3-Furylmethyl)-nordesomorphine-hydrochloride-monohydrate (Wa… Expand
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