Noscapine

Known as: 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (S-(R*,S*))-, Narcotine, Noscapine [Chemical/Ingredient] 
A phthalide isoquinoline non-narcotic alkaloid derived from the opium poppy Papaver somniferum, with mild analgesic, antitussive, and potential… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Noscapine is an antitumor alkaloid from opium poppy that binds tubulin, arrests metaphase, and induces apoptosis in dividing… (More)
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2012
2012
Noscapine is a benzylisoquinoline alkaloid produced in opium poppy (Papaver somniferum) and other members of the Papaveraceae. It… (More)
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2010
2010
AIMS To investigate the inhibition potential and kinetic information of noscapine to seven CYP isoforms and extrapolate in vivo… (More)
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2004
2004
The opium alkaloid noscapine is a commonly used antitussive agent available in Europe, Asia, and South America. Although the… (More)
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Highly Cited
2002
Highly Cited
2002
Cellular microtubules, polymers of tubulin, alternate relentlessly between phases of growth and shortening. We now show that… (More)
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Highly Cited
2000
Highly Cited
2000
Noscapine, a phthalideisoquinoline alkaloid derived from opium, has been used as an oral anti-tussive agent and has shown very… (More)
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2000
2000
Noscapine, an antitussive drug, has been previously shown to inhibit the growth of cultured tumor cells and tumors implanted in… (More)
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Highly Cited
1998
Highly Cited
1998
An alkaloid from opium, noscapine, is used as an antitussive drug and has low toxicity in humans and mice. We show that noscapine… (More)
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1990
1990
The relative bioavailability in 20 healthy volunteers of 100 mg, 200 mg and 300 mg tablets of noscapine and 200 mg as a solution… (More)
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1982
1982
Noscapine was administered to five healthy volunteers in a randomized crossover design, as an intravenous infusion of 66 mg, and… (More)
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