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simvastatin acid

Known as: Simvastatin Carboxylic Acid, 1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-, (1S-(1alpha(betaS*,deltaS*),2alpha,6beta,8beta,8aalpha))-, Tenivastatin 
 
National Institutes of Health

Papers overview

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Review
2008
Review
2008
HMG-CoA reductase inhibitors (statins) dose-dependently lower both the level of low-density lipoprotein cholesterol and risk of… Expand
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Highly Cited
2006
Highly Cited
2006
Background and objective Organic anion transporting polypeptide 1B1 (OATP1B1) is an uptake transporter located at the sinusoidal… Expand
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Review
2006
Review
2006
Lipid‐lowering drugs, especially 3‐hydroxy‐3‐methylglutaryl–coenzyme A inhibitors (statins), are widely used in the treatment and… Expand
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Highly Cited
2004
Highly Cited
2004
  • B. Kang, J. Lee, +5 authors S. Cho
  • International journal of pharmaceutics
  • 2004
  • Corpus ID: 36055586
The main purpose of this work is to prepare self-microemulsifying drug delivery system (SMEDDS) for oral bioavailability… Expand
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Highly Cited
2004
Highly Cited
2004
  • T. Jacobson
  • The American journal of cardiology
  • 2004
  • Corpus ID: 20286685
Three-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors (statins) are first-line treatments for hypercholesterolemia… Expand
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Highly Cited
2004
Highly Cited
2004
AIMS Simvastatin, a substrate for CYP3A4, is extensively metabolized during the first pass. Our aim was to investigate the effect… Expand
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Highly Cited
2000
Highly Cited
2000
Concomitant treatment with simvastatin and gemfibrozil, two lipid‐lowering drugs, has been associated with occurrence of myopathy… Expand
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Highly Cited
1998
Highly Cited
1998
Simvastatin is a cholesterol‐lowering agent that is metabolized through CYP3A4. We studied the effect of grapefruit juice on the… Expand
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Highly Cited
1998
Highly Cited
1998
To study the effects of erythromycin and verapamil on the pharmacokinetics of simvastatin, an inhibitor of 3‐hydroxy‐3… Expand
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Highly Cited
1998
Highly Cited
1998
Itraconazole increases the risk of skeletal muscle toxicity of some 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase… Expand
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