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simaomicin alpha

 
National Institutes of Health

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Isoquinolines

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2009
2009
Simaomicin α, a polycyclic xanthone, induces G1 arrest with suppression of retinoblastoma protein phosphorylation
Recent progress in cancer biology research has shown that abnormal proliferation in tumor cells can be attributed to aberrations… Expand
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2008
2008
Simaomicin α: Effects on the Cell Cycle of Synchronized, Cultured Plasmodium falciparum
Simaomicin α shows potent antimalarial activity in vitro and is known to be a cell-cycle effector. As erythrocytic schizogony of… Expand
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2007
2007
Selective and Potent In Vitro Antimalarial Activities Found in Four Microbial Metabolites
Antimalarial activities have been identified in four microbial metabolites through a screening programme of existing compounds in… Expand
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2004
2004
Selective inhibition of bleomycin-induced G2 cell cycle checkpoint by simaomicin alpha.
Human T-cell leukemia-derived Jurkat cells are known to be defective in the G1 checkpoint. DNA-damaging agent bleomycin arrests… Expand
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1990
1990
Simaomicin (LL-D42067), a novel antibiotic from Actinomadura madurae. I. Taxonomy, fermentation and biological activity.
A new antibacterial antibiotic, designated simaomicin alpha (LL-D42067 alpha) was isolated from the fermentation broth of an… Expand
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