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- Publications
- Influence
In vitro and in vivo antimalarial activities of a non-glycosidic 18-membered macrolide antibiotic, borrelidin, against drug-resistant strains of Plasmodia.
- K. Otoguro, H. Ui, +8 authors S. O̅mura
- Chemistry, Medicine
- The Journal of antibiotics
- 25 August 2003
Sir: In the course of our screening program to discover antimalarial antibiotics from soil microorganisms which are active against drug-resistant parasites in vitro and in vivo, we previously… Expand
Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum
- A. Ishiyama, M. Iwatsuki, +5 authors K. Otoguro
- Biology, Medicine
- The Journal of Antibiotics
- 25 May 2011
Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum
New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives.
- Y. Toriizuka, Eri Kinoshita, +6 authors H. Takayama
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 15 December 2008
A new lycorine derivative LT1 (4) was isolated from the aerial part and bulbs of Lycoris traubii Hayward (Amaryllidaceae). Its structure including absolute configuration was established by… Expand
In vitro antimalarial activity of biflavonoids from Wikstroemia indica.
- Shinyu Nunome, A. Ishiyama, +4 authors S. O̅mura
- Biology, Medicine
- Planta medica
- 2004
In our investigation of in vitro antimalarial screening of medicinal herbal extracts, the n-BuOH extract from the root of Wikstroemia indica showed a potent inhibitory effect. Fractionation of the… Expand
Antitrypanosomal activity of some pregnane glycosides isolated from Caralluma species.
- E. Abdel-Sattar, N. Shehab, +5 authors H. Yamada
- Biology, Medicine
- Phytomedicine : international journal of…
- 1 June 2009
Pregnane glycosides previously isolated from genus Caralluma (C. Penicillata, C. tuberculata and C. russelliana) were tested for their antitrypanosomal activity. Penicilloside E showed the highest… Expand
Penicillium viticola, a new species isolated from a grape in Japan
- Kenichi Nonaka, R. Masuma, M. Iwatsuki, K. Shiomi, K. Otoguro, S. O̅mura
- Biology
- 1 September 2011
A new monoverticillate Penicillium species (subgenus Aspergilloides Dierckx), Penicillium viticola, was isolated from a grape cultivated in Yamanashi Prefecture, Japan. Morphologically, P. viticola… Expand
In vitro antimalarial activity of prenylated flavonoids from Erythrina fusca
- Pranorm Khaomek, C. Ichino, +8 authors H. Yamada
- Chemistry, Medicine
- Journal of Natural Medicines
- 30 January 2008
Ethyl acetate (EtOAc) extract from the stem bark of Erythrina fusca showed a antimalarial activity against the multi-drug-resistant strain (K1) of Plasmodium falciparum, and six flavonoids,… Expand
Antiplasmodial and antitrypanosomal activity of plants from the Kingdom of Saudi Arabia
- E. Abdel-Sattar, F. Harraz, +6 authors H. Yamada
- Biology, Medicine
- Journal of Natural Medicines
- 1 April 2009
The antiplasmodial and antitrypanosomal activity of the methanol extracts of 42 plants collected from the Kingdom of Saudi Arabia and some fractions obtained thereof were evaluated. The… Expand
Zamamidine C, 3,4-dihydro-6-hydroxy-10,11-epoxymanzamine A, and 3,4-dihydromanzamine J N-oxide, new manzamine alkaloids from sponge Amphimedon sp.
- M. Yamada, Y. Takahashi, +6 authors J. Kobayashi
- Chemistry
- 14 March 2009
Abstract New manzamine alkaloids, zamamidine C ( 1 ), 3,4-dihydro-6-hydroxy-10,11-epoxymanzamine A ( 2 ), and 3,4-dihydromanzamine J N -oxide ( 3 ), have been isolated from an Okinawan marine sponge… Expand
Potent antimalarial activities of polyether antibiotic, X-206.
- K. Otoguro, A. Kohana, +5 authors S. O̅mura
- Medicine, Biology
- The Journal of antibiotics
- 25 August 2001
In the course of our screening program to discover antimalarial antibiotics, which are active against drug resistant Plasmodium falciparum in vitro and rodents infected with P. berghei in vivo, from… Expand