K. Otoguro

Publications119
h-index28
Citations2,687
Highly Influential Citations78
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In vitro and in vivo antimalarial activities of a non-glycosidic 18-membered macrolide antibiotic, borrelidin, against drug-resistant strains of Plasmodia.
Sir: In the course of our screening program to discover antimalarial antibiotics from soil microorganisms which are active against drug-resistant parasites in vitro and in vivo, we previously… Expand
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Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum
Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum
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New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives.
A new lycorine derivative LT1 (4) was isolated from the aerial part and bulbs of Lycoris traubii Hayward (Amaryllidaceae). Its structure including absolute configuration was established by… Expand
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In vitro antimalarial activity of biflavonoids from Wikstroemia indica.
In our investigation of in vitro antimalarial screening of medicinal herbal extracts, the n-BuOH extract from the root of Wikstroemia indica showed a potent inhibitory effect. Fractionation of the… Expand
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Antitrypanosomal activity of some pregnane glycosides isolated from Caralluma species.
Pregnane glycosides previously isolated from genus Caralluma (C. Penicillata, C. tuberculata and C. russelliana) were tested for their antitrypanosomal activity. Penicilloside E showed the highest… Expand
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Penicillium viticola, a new species isolated from a grape in Japan
A new monoverticillate Penicillium species (subgenus Aspergilloides Dierckx), Penicillium viticola, was isolated from a grape cultivated in Yamanashi Prefecture, Japan. Morphologically, P. viticola… Expand
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In vitro antimalarial activity of prenylated flavonoids from Erythrina fusca
Ethyl acetate (EtOAc) extract from the stem bark of Erythrina fusca showed a antimalarial activity against the multi-drug-resistant strain (K1) of Plasmodium falciparum, and six flavonoids,… Expand
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Antiplasmodial and antitrypanosomal activity of plants from the Kingdom of Saudi Arabia
The antiplasmodial and antitrypanosomal activity of the methanol extracts of 42 plants collected from the Kingdom of Saudi Arabia and some fractions obtained thereof were evaluated. The… Expand
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Zamamidine C, 3,4-dihydro-6-hydroxy-10,11-epoxymanzamine A, and 3,4-dihydromanzamine J N-oxide, new manzamine alkaloids from sponge Amphimedon sp.
Abstract New manzamine alkaloids, zamamidine C ( 1 ), 3,4-dihydro-6-hydroxy-10,11-epoxymanzamine A ( 2 ), and 3,4-dihydromanzamine J N -oxide ( 3 ), have been isolated from an Okinawan marine sponge… Expand
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Potent antimalarial activities of polyether antibiotic, X-206.
In the course of our screening program to discover antimalarial antibiotics, which are active against drug resistant Plasmodium falciparum in vitro and rodents infected with P. berghei in vivo, from… Expand
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