sepiapterin

Known as: 2-amino-6-(S)-lactoyl-7,8-dihydro-4(3H)- pteridinone, 4(3H)-pteridinone, 2-amino-7,8-dihydro-6-((2S)-2-hydroxy-1-oxopropyl)-, sepia-pterin 
 
National Institutes of Health

Papers overview

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Review
2011
Review
2011
BH4 (6R-L-erythro-5,6,7,8-tetrahydrobiopterin) is an essential cofactor of a set of enzymes that are of central metabolic… (More)
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Highly Cited
2009
Highly Cited
2009
Endothelial nitric oxide synthase (eNOS) uncoupling is a mechanism that leads to endothelial dysfunction. Previously, we reported… (More)
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2006
2006
Tetrahydrobiopterin (BH(4)) is an essential cofactor for several enzymes, including all three forms of nitric oxide synthases… (More)
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2002
2002
Sepiapterin reductase (SR) deficiency was recently described in patients with a severe biogenic amine deficiency presenting… (More)
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Highly Cited
2002
Highly Cited
2002
Augmentation of superoxide levels has been linked to impaired relaxation in hypertension, diabetes and hypercholesterolaemia… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Altered endothelial cell nitric oxide (NO(*)) production in atherosclerosis may be due to a reduction of intracellular… (More)
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Review
2000
Review
2000
Tetrahydrobiopterin (BH(4)) cofactor is essential for various processes, and is present in probably every cell or tissue of… (More)
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Highly Cited
2000
Highly Cited
2000
Ascorbic acid enhances NO bioactivity in patients with vascular disease through unclear mechanism(s). We investigated the role of… (More)
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Highly Cited
1992
Highly Cited
1992
Nitric oxide (NO) synthesis is induced in vascular smooth muscle cells by lipopolysaccharide (LPS) where it appears to mediate a… (More)
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Highly Cited
1990
Highly Cited
1990
Interferon-gamma induces tetrahydrobiopterin biosynthesis in human cells and cell lines. Macrophages are peculiar in the… (More)
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