sazetidine-A
National Institutes of Health
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Neuronal acetylcholine receptors mediate the addictive effects of nicotine and may also be involved in alcohol addiction…
Chronic nicotine administration increases α4β2 neuronal nicotinic acetylcholine receptor (nAChR) density in brain. This up…
Alcoholism is a complex heterogeneous disease and a number of neurotransmitter and neuromodulator systems have been implicated in…
We have developed a new radioligand binding assay method to measure the concentration of nonradiolabeled drugs in the brain ex…
Nicotine and nicotinic agonists have been shown to improve attentional function. Nicotinic receptors are easily desensitized, and…
Adequate treatment of tobacco addiction remains problematic. Part of the problem with treatment is a poor understanding of the…
Background:The use of nicotinic agonists for analgesia is limited by their unacceptable side effects. Sazetidine-A is a new…