sargramostim

Known as: rhu GM-CFS, sargramostim [Chemical/Ingredient], Sagramostim 
A recombinant therapeutic agent chemically identical to endogenous human GM-CSF except a leucine substitution in position 23. Binding to specific… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1958-2017
010020030019582017

Papers overview

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Highly Cited
2014
Highly Cited
2014
IMPORTANCE Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) blockade with ipilimumab prolongs survival in patients with… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Preclinical and preliminary clinical data indicate that ch14.18, a monoclonal antibody against the tumor-associated… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Sargramostim, granulocyte-macrophage colony-stimulating factor, a hematopoietic growth factor, stimulates cells of the… (More)
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Highly Cited
2004
Highly Cited
2004
Tumor vaccines have shown promise in early clinical trials. Among them, tumor cells genetically engineered to secrete… (More)
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Highly Cited
1999
Highly Cited
1999
As dendritic cells (DC) are rare populations in all organs, their generation from hematopoietic precursors in large quantities… (More)
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Highly Cited
1999
Highly Cited
1999
Tumor cells gene-modified to produce GM-CSF potently stimulate antitumor immune responses, in part, by causing the growth and… (More)
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Highly Cited
1996
Highly Cited
1996
The novel cytokine interferon-gamma-inducing factor (IGIF) augments natural killer (NK) cell activity in cultures of human… (More)
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Highly Cited
1991
Highly Cited
1991
The cDNA for human stem cell factor (hSCF) has been cloned and expressed in mammalian and bacterial hosts and recombinant protein… (More)
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Highly Cited
1986
Highly Cited
1986
A purified recombinant human granulocyte-macrophage colony stimulating factor (rH GM-CSF) was a powerful stimulator of mature… (More)
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Highly Cited
1985
Highly Cited
1985
Clones of complementary DNA encoding the human lymphokine known as granulocyte-macrophage colony-stimulating factor (GM-CSF) were… (More)
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