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sargramostim

Known as: rhu GM-CFS, sargramostim [Chemical/Ingredient], Sagramostim 
A recombinant therapeutic agent chemically identical to endogenous human GM-CSF except a leucine substitution in position 23. Binding to specific… 
National Institutes of Health

Related topics

Related topics

28 relations
CSF2 geneCSF2 wt AlleleCytokine Receptor ActivationDrug Allergy

Broader (3)

Granulocyte-Macrophage Colony-Stimulating FactorRecombinant Granulocyte-Macrophage Colony-Stimulating FactorsRecombinant Proteins

Narrower (1)

Leukine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1997
Review
1997
Clinical and pathological response to primary chemotherapy in operable breast cancer.
Highly Cited
1996
Highly Cited
1996
Intensified antitumor immunity by a cancer vaccine that produces granulocyte-macrophage colony-stimulating factor plus interleukin 4.
Vaccination with irradiated tumor cells genetically modified to secrete granulocyte-macrophage colony-stimulating factor (GM-CSF… 
Highly Cited
1996
Highly Cited
1996
Interleukin-3 cooperates with tumor necrosis factor alpha for the development of human dendritic/Langerhans cells from cord blood CD34+ hematopoietic progenitor cells.
We have previously shown that tumor necrosis factor (TNF)alpha strongly potentiates the granulocyte-macrophage colony-stimulating… 
Highly Cited
1991
Highly Cited
1991
Mast cell growth factor (c-kit ligand) enhances cytokine stimulation of proliferation of the human factor-dependent cell line, M07e.
Murine mast cell growth factor (muMGF), a c-kit ligand, has additive to greater-than-additive effects on in vitro colony… 
Highly Cited
1991
Highly Cited
1991
Involvement of tyrosine kinases in the activation of human peripheral blood neutrophils by granulocyte-macrophage colony-stimulating factor.
The aim of the present study is to evaluate the involvement of human neutrophil tyrosine kinase(s) in the signal transduction… 
Highly Cited
1990
Highly Cited
1990
Regulation of surface expression of the granulocyte/macrophage colony-stimulating factor receptor in normal human myeloid cells.
Recombinant human granulocyte/macrophage colony-stimulating factor (GM-CSF) exerts stimulatory effects on hematopoietic cells… 
Highly Cited
1988
Highly Cited
1988
Interdependence of the radioprotective effects of human recombinant interleukin 1 alpha, tumor necrosis factor alpha, granulocyte colony-stimulating factor, and murine recombinant granulocyte…
Interleukin 1 alpha (IL-1 alpha), tumor necrosis factor alpha (TNF alpha), granulocyte-colony-stimulating factor (G-CSF), and… 
Highly Cited
1986
Highly Cited
1986
Effects of recombinant human GM-CSF on proliferation of clonogenic cells in acute myeloblastic leukemia.
Proliferation of acute myeloblastic leukemia (AML) cells in vitro is limited in most cases to a small subset of blasts that have… 
Highly Cited
1986
Highly Cited
1986
Effects of recombinant GM-CSF on the blast cells of acute myeloblastic leukemia.
The effects of recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) were compared to those of media conditioned… 
Review
1986
Review
1986
Regulation of expression of human granulocyte/macrophage colony-stimulating factor.
Colony-stimulating factors (CSFs) are glycoproteins that stimulate the growth of hematopoietic progenitors and enhance the… 
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