ribonuclease T2 activity

Known as: RNase Ms activity, ribonuclease M activity, RNase (non-base specific) activity 
Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Antiviral innate immunity is initiated in response to RNA molecules that are produced in virus-infected cells. These RNAs… (More)
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Highly Cited
2004
Highly Cited
2004
Inherently unstable mRNAs contain AU-rich elements (AREs) in their 3' untranslated regions that act as mRNA stability… (More)
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Highly Cited
2003
Highly Cited
2003
RNA interference can be considered as an antisense mechanism of action that utilizes a double-stranded RNase to promote… (More)
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Highly Cited
2003
Highly Cited
2003
Eukaryotic mRNA stability can be influenced by AU-rich elements (AREs) within mRNA primary sequences. Tristetraprolin (TTP) is a… (More)
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Highly Cited
2003
Highly Cited
2003
The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific… (More)
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Review
1999
Review
1999
RNase H-competent phosphorothioates (S-DNAs) have dominated the antisense field in large part because they offer reasonable… (More)
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Highly Cited
1997
Highly Cited
1997
The 2-5A system contributes to the antiviral effect of interferons through the synthesis of 2-5A and its activation of the… (More)
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Highly Cited
1996
Highly Cited
1996
The removal of the mRNA poly(A) tail in the yeast Saccharomyces cerevisiae is stimulated by the poly(A)-binding protein (Pab1p… (More)
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Highly Cited
1995
Highly Cited
1995
The 2-5A/RNase L system is considered as a central pathway of interferon (IFN) action and could possibly play a more general… (More)
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Highly Cited
1993
Highly Cited
1993
RNase MRP is a site-specific ribonucleoprotein endoribonuclease that cleaves RNA from the mitochondrial origin of replication in… (More)
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