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Ribonuclease T1 activity

Known as: ribonuclease N1, RNase N2 activity, binase activity 
Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate… Expand
National Institutes of Health

Related topics

Related topics

5 relations
RNase GRibonuclease F1Ribonuclease T1ribonuclease T2 activity
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
The 2′-5′-Oligoadenylate Synthetase 3 Enzyme Potently Synthesizes the 2′-5′-Oligoadenylates Required for RNase L Activation
ABSTRACT The members of the oligoadenylate synthetase (OAS) family of proteins are antiviral restriction factors that target a… Expand
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2014
2014
Cell-Type-Specific Effects of RNase L on Viral Induction of Beta Interferon
ABSTRACT The interferon (IFN)-inducible antiviral state is mediated in part by the 2′,5′-oligoadenylate (2-5A) synthetase (OAS… Expand
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2014
2014
RNase L Targets Distinct Sites in Influenza A Virus RNAs
ABSTRACT Influenza A virus (IAV) infections are influenced by type 1 interferon-mediated antiviral defenses and by viral… Expand
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2008
2008
Cancer-suppressive effect of RNase A and DNase I
108 The ability of RNase A and DNase I to suppress the growth of malignant tumors and prevent its metastasizing was studied. It… Expand
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2005
2005
2‐5A induces a conformational change in the ankyrin‐repeat domain of RNase L
RNase L is responsible for the 2‐5A host defense system, an RNA degradation pathway present in cells of higher vertebrates that… Expand
2000
2000
Selective RNA cleavage by isolated RNase L activated with 2-5A antisense chimeric oligonucleotides.
Publisher Summary Cellular ribonucleases often play essential roles in the mechanism of action of antisense oligonucleotides… Expand
1995
1995
Capillary enzymophoresis of nucleic acid fragments using coupled capillary electrophoresis and capillary enzyme microreactors having surface‐immobilized RNA‐modifying enzymes
This report describes the coupling of capillary enzyme reactors to capillary electrophoresis, which is termed capillary… Expand
1994
1994
Crystallographic study of Glu58Ala RNase T1 x 2'-guanosine monophosphate at 1.9-A resolution.
Glu58 is known to participate in phosphodiester transesterification catalyzed by the enzyme RNase T1. For Glu58 RNase T1, an… Expand
Highly Cited
1972
Highly Cited
1972
Polyadenylic acid at the 3'-terminus of poliovirus RNA.
  • Y. Yogo, E. Wimmer
  • Proceedings of the National Academy of Sciences…
  • 1972
    • Corpus ID: 11753393
Poliovirus RNA that has been derivatized at the 3'-end with NaIO(4)-NaB(3)H(4) yields, after hydrolysis with alkali or RNase T2… Expand
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1970
1970
pH dependence of the RNase T1 action on nucleoside 2',- 3'-cyclic phosphates.
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