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Ribonuclease T1 activity

Known as: ribonuclease N1, RNase N2 activity, binase activity 
Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate… Expand
National Institutes of Health

Related topics

Related topics

5 relations
RNase GRibonuclease F1Ribonuclease T1ribonuclease T2 activity
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activation.
Prior studies have demonstrated that the mouse hepatitis virus (MHV) A59 strain ns2 protein is a member of the 2H phosphoesterase… Expand
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2014
2014
The 2′-5′-Oligoadenylate Synthetase 3 Enzyme Potently Synthesizes the 2′-5′-Oligoadenylates Required for RNase L Activation
ABSTRACT The members of the oligoadenylate synthetase (OAS) family of proteins are antiviral restriction factors that target a… Expand
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2014
2014
Cell-Type-Specific Effects of RNase L on Viral Induction of Beta Interferon
ABSTRACT The interferon (IFN)-inducible antiviral state is mediated in part by the 2′,5′-oligoadenylate (2-5A) synthetase (OAS… Expand
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2014
2014
RNase L Targets Distinct Sites in Influenza A Virus RNAs
ABSTRACT Influenza A virus (IAV) infections are influenced by type 1 interferon-mediated antiviral defenses and by viral… Expand
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2008
2008
Cancer-suppressive effect of RNase A and DNase I
108 The ability of RNase A and DNase I to suppress the growth of malignant tumors and prevent its metastasizing was studied. It… Expand
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2005
2005
2-5A induces a conformational change in the ankyrin-repeat domain of RNase L.
RNase L is responsible for the 2-5A host defense system, an RNA degradation pathway present in cells of higher vertebrates that… Expand
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2000
2000
Selective RNA cleavage by isolated RNase L activated with 2-5A antisense chimeric oligonucleotides.
Publisher Summary Cellular ribonucleases often play essential roles in the mechanism of action of antisense oligonucleotides… Expand
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1995
1995
Capillary enzymophoresis of nucleic acid fragments using coupled capillary electrophoresis and capillary enzyme microreactors having surface-immobilized RNA-modifying enzymes.
This report describes the coupling of capillary enzyme reactors to capillary electrophoresis, which is termed capillary… Expand
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Highly Cited
1972
Highly Cited
1972
Polyadenylic acid at the 3'-terminus of poliovirus RNA.
Poliovirus RNA that has been derivatized at the 3'-end with NaIO(4)-NaB(3)H(4) yields, after hydrolysis with alkali or RNase T2… Expand
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1967
1967
Cytochemische Untersuchungen an Puffs isolierter Speicheldrüsen-Chromosomen von Chironomus
Enzymatic digestion experiments on unfixed isolated salivary gland chromosomes of Chironomus tentans combined with specific… Expand
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