FAQ

Ribonuclease T1 activity

Known as: ribonuclease N1, RNase N2 activity, binase activity 
Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2015
051019662015

Related topics

Related topics

5 relations
RNase GRNase Sa activityRibonuclease F1Ribonuclease T1
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Related mentions per year

Related mentions per year

1961-2017
1960198020002020
Ribonuclease T1 activity
Ribonuclease T1
ribonuclease T2 activity
RNase Sa activity
Ribonuclease F1
RNase G

Papers overview

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2004
2004
Rapid analysis of CpG methylation patterns using RNase T1 cleavage and MALDI-TOF.
Here, we introduce a method for the fast and accurate analysis of DNA methylation based on bisulfite-treated DNA. The target… (More)
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2001
2001
Deciphering the mechanism of RNase T1.
 
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2000
2000
Mechanism of RNase T1: concerted triester-like phosphoryl transfer via a catalytic three-centered hydrogen bond.
BACKGROUND The microscopic events of ribonuclease (RNase) catalyzed phosphoryl transfer reactions are still a matter of debate in… (More)
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2000
2000
Analysis of a water mediated protein-protein interactions within RNase T1.
Buried and well-ordered solvent molecules are an integral part of each folded protein. For a few individual water molecules, the… (More)
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1999
1999
Conserved water molecules in a large family of microbial ribonucleases.
We systematically analyzed the crystallographically determined water molecules of all known structures of RNase T1 and compared… (More)
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1999
1999
Dissection of the structural and functional role of a conserved hydration site in RNase T1.
The reoccurrence of water molecules in crystal structures of RNase T1 was investigated. Five waters were found to be invariant in… (More)
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1996
1996
Are turns required for the folding of ribonuclease T1?
Ribonuclease T1 (RNase T1) is a small, globular protein of 104 amino acids for which extensive thermodynamic and structural… (More)
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1993
1993
Stability and folding kinetics of ribonuclease T1 are strongly altered by the replacement of cis-proline 39 with alanine.
The refolding of ribonuclease T1 involves two major slow processes that exhibit properties of prolyl isomerization reactions. A… (More)
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1992
1992
Contribution of hydrogen bonding to the conformational stability of ribonuclease T1.
For 30 years, the prevailing view has been that the hydrophobic effect contributes considerably more than hydrogen bonding to the… (More)
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1987
1987
Two histidine residues are essential for ribonuclease T1 activity as is the case for ribonuclease A.
Ribonuclease T1 (RNase T1, EC 3.1.27.3) is a guanosine-specific ribonuclease that cleaves the 3',5'-phosphodiester linkage of… (More)
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