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renzapride

Known as: 4-amino-5-chloro-2-methoxy-N-(1-azabicyclo-(3.3.1)-non-4-yl)benzamide, Benzamide, 4-amino-N-1-azabicyclo(3.3.1)non-4-yl-5-chloro-2-methoxy-, monohydrochloride, endo-(+-)- 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

BRL 24924

Broader (3)

BenzamidesBridged Bicyclo Compounds, HeterocyclicSerotonin Antagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Systematic review: cardiovascular safety profile of 5-HT4 agonists developed for gastrointestinal disorders
The nonselective 5‐HT4 receptor agonists, cisapride and tegaserod have been associated with cardiovascular adverse events (AEs). 
Highly Cited
2010
Highly Cited
2010
Enteric Nervous System in the Small Intestine: Pathophysiology and Clinical Implications
The digestive system is endowed with its own, local nervous system, referred to as the enteric nervous system (ENS). Given the… 
Review
2009
Review
2009
Efficacy of 5-HT3 Antagonists and 5-HT4 Agonists in Irritable Bowel Syndrome: Systematic Review and Meta-Analysis
OBJECTIVES:Irritable bowel syndrome (IBS) is a chronic functional disorder. 5-Hydroxytryptamine (5-HT) is a key modulator of… 
Review
2006
Review
2006
Systematic review: the efficacy of treatments for irritable bowel syndrome – a European perspective
Irritable bowel syndrome (IBS) is a common, chronic disorder, characterized by abdominal pain/discomfort, bloating and altered… 
Highly Cited
1997
Highly Cited
1997
Analysis of the Ligand Binding Site of the 5-HT3 Receptor Using Site Directed Mutagenesis: Importance of Glutamate 106
Highly Cited
1997
Highly Cited
1997
Molecular and functional characterization of a 5‐HT4 receptor cloned from human atrium
Highly Cited
1996
Highly Cited
1996
Compounds possessing 5-HT3 receptor antagonistic activity inhibit intestinal propulsion in mice.
Highly Cited
1992
Highly Cited
1992
5-Hydroxytryptamine stimulates cyclic AMP formation in the tunica muscularis mucosae of the rat oesophagus via 5-HT4 receptors.
Highly Cited
1991
Highly Cited
1991
Identification of putative 5-HT4 receptors in guinea-pig ascending colon.
Highly Cited
1991
Highly Cited
1991
Prokinetic benzamides stimulate peristaltic activity in the isolated guinea pig ileum by activation of 5-HT4 receptors.
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