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renzapride

Known as: 4-amino-5-chloro-2-methoxy-N-(1-azabicyclo-(3.3.1)-non-4-yl)benzamide, Benzamide, 4-amino-N-1-azabicyclo(3.3.1)non-4-yl-5-chloro-2-methoxy-, monohydrochloride, endo-(+-)- 
 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

BRL 24924

Broader (3)

BenzamidesBridged Bicyclo Compounds, HeterocyclicSerotonin Antagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Enteric Nervous System in the Small Intestine: Pathophysiology and Clinical Implications
The digestive system is endowed with its own, local nervous system, referred to as the enteric nervous system (ENS). Given the… Expand
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2010
2010
Clinical trial: renzapride treatment of women with irritable bowel syndrome and constipation – a double‐blind, randomized, placebo‐controlled, study
Aliment Pharmacol Ther 31, 979–990 
Highly Cited
2006
Highly Cited
2006
Pilot study of the efficacy of renzapride on gastrointestinal motility and symptoms in patients with constipation‐predominant irritable bowel syndrome
To investigate the efficacy and safety of renzapride, a potent 5‐hydroxytryptamine type‐4 receptor full agonist and 5… Expand
Review
2005
Review
2005
Basic and clinical pharmacology of new motility promoting agents
Abstract  Recent research has provided new information about drugs that could be used to treat functional motility disorders… Expand
Highly Cited
2004
Highly Cited
2004
Effect of renzapride on transit in constipation-predominant irritable bowel syndrome.
BACKGROUND & AIMS The aim of this study was to evaluate the dose-ranging pharmacodynamic effects of renzapride, a 5… Expand
Highly Cited
1998
Highly Cited
1998
Cloning, Expression, and Pharmacology of Four Human 5‐Hydroxytryptamine4 Receptor Isoforms Produced by Alternative Splicing in the Carboxyl Terminus
Abstract: We report here the molecular cloning of three new splice variants of the human serotonin 5‐hydroxytryptamine4 (h5‐HT4… Expand
Highly Cited
1992
Highly Cited
1992
Serotonin increases calcium current in human atrial myocytes via the newly described 5-hydroxytryptamine4 receptors.
In various species, including humans, 5-hydroxytryptamine (5-HT) has been shown to exert positive chronotropic and inotropic… Expand
Highly Cited
1991
Highly Cited
1991
Peristalsis evoked by 5‐HT and renzapride: evidence for putative 5‐HT4 receptor activation
The effect of 5‐hydroxytryptamine and renzapride was studied on the peristaltic reflex elicited in vitro in the guinea‐pig ileum… Expand
Highly Cited
1991
Highly Cited
1991
Identification of putative 5-HT4 receptors in guinea-pig ascending colon.
Experiments were carried out to characterise pharmacologically a neuronal, non-5-HT3, 5-hydroxytryptamine (5-HT) receptor in… Expand
Highly Cited
1990
Highly Cited
1990
Characterization of 5‐HT3 and ‘atypical’ 5‐HT receptors mediating guinea‐pig ileal contractions in vitro
1 Neuronal 5‐hydroxytryptamine (5‐HT) receptors mediating contraction of guinea‐pig ileal segments have been characterized in… Expand
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