recurrent childhood brain stem glioma

Known as: Relapsed Pediatric Glioma of Brainstem, Relapsed Pediatric Glioma of the Brain Stem, glioma, recurrent pediatric brain stem 
The reemergence of brain stem glioma in childhood after a period of remission.
National Institutes of Health

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BrainBrain StemCentral Nervous SystemInfratentorial brain structure
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Papers overview

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Review
2017
Review
2017
First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer.
BACKGROUND Nivolumab has been associated with longer overall survival than docetaxel among patients with previously treated non… (More)
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Highly Cited
2013
Highly Cited
2013
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
Mice carrying mutations in multiple genes are traditionally generated by sequential recombination in embryonic stem cells and/or… (More)
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Highly Cited
2012
Highly Cited
2012
Somatic Histone H3 Alterations in Paediatric Diffuse Intrinsic Pontine Gliomas and Non-Brainstem Glioblastomas
To identify somatic mutations in pediatric diffuse intrinsic pontine glioma (DIPG), we performed whole-genome sequencing of DNA… (More)
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Highly Cited
2006
Highly Cited
2006
Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells
Polycomb group proteins are essential for early development in metazoans, but their contributions to human development are not… (More)
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Highly Cited
2006
Highly Cited
2006
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
Oct4 and Nanog are transcription factors required to maintain the pluripotency and self-renewal of embryonic stem (ES) cells… (More)
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Highly Cited
2003
Highly Cited
2003
BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3
The cytokine leukemia inhibitory factor (LIF) drives self-renewal of mouse embryonic stem (ES) cells by activating the… (More)
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Highly Cited
2003
Highly Cited
2003
Dicer is essential for mouse development
To address the biological function of RNA interference (RNAi)-related pathways in mammals, we disrupted the gene Dicer1 in mice… (More)
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Highly Cited
2002
Highly Cited
2002
Whole Brain Segmentation Automated Labeling of Neuroanatomical Structures in the Human Brain
We present a technique for automatically assigning a neuroanatomical label to each voxel in an MRI volume based on probabilistic… (More)
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Highly Cited
2000
Highly Cited
2000
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
Cell fate during development is defined by transcription factors that act as molecular switches to activate or repress specific… (More)
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Highly Cited
2000
Highly Cited
2000
Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro
We describe the derivation of pluripotent embryonic stem (ES) cells from human blastocysts. Two diploid ES cell lines have been… (More)
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