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recombinase

Known as: Recombinases, Recombinases [Chemical/Ingredient] 
A broad category of enzymes that are involved in the process of GENETIC RECOMBINATION.
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (4)

CcrC protein, Staphylococcus aureusMerCreMer recombinaseResolvasesXerS tyrosine recombinase, Streptococcus pneumoniae R6
In BloodProcess of secretionRec A Recombinasesantagonists & inhibitors
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Broader (1)

nucleotidyltransferase

Papers overview

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Highly Cited
2007
Highly Cited
2007
Targeting Cre Recombinase to Specific Neuron Populations with Bacterial Artificial Chromosome Constructs
Transgenic mouse lines are characterized with Cre recombinase driven by promoters of CNS-specific genes using bacterial… Expand
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Highly Cited
2004
Highly Cited
2004
Novel Type V Staphylococcal Cassette Chromosome mec Driven by a Novel Cassette Chromosome Recombinase, ccrC
ABSTRACT Staphylococcal cassette chromosome mec (SCCmec) is a mobile genetic element composed of the mec gene complex, which… Expand
Review
2004
Review
2004
Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice.
Site-specific recombinase systems (Cre-loxP, Flp-FRT, and phi C31-att) are transforming both forward and reverse genetics in mice… Expand
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Highly Cited
2002
Highly Cited
2002
Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer
Summary: We have used a Prx1 limb enhancer to drive expression of Cre Recombinase in transgenic mice. This regulatory element… Expand
Highly Cited
2000
Highly Cited
2000
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products.
We have developed a simple and highly efficient method to disrupt chromosomal genes in Escherichia coli in which PCR primers… Expand
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Highly Cited
2000
Highly Cited
2000
Widespread recombinase expression using FLPeR (Flipper) mice
Summary: As conditional genetic strategies advance, the need for multiple site‐specific recombinase systems has emerged. To meet… Expand
Review
1998
Review
1998
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
The ability to generate specific genetic modifications in mice provides a powerful approach to assess gene function. When genetic… Expand
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Highly Cited
1997
Highly Cited
1997
Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains.
Ligand-dependent chimeric Cre recombinases are powerful tools to induce specific DNA rearrangements in cultured cells and in mice… Expand
Highly Cited
1989
Highly Cited
1989
The FLP recombinase of yeast catalyzes site-specific recombination in the drosophila genome
We have transferred the site-specific recombination system of the yeast 2 micron plasmid, the FLP recombinase and its… Expand
Highly Cited
1988
Highly Cited
1988
Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.
The Cre protein encoded by the coliphage P1 is a 38-kDa protein that efficiently promotes both intra- and intermolecular synapsis… Expand
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