recombinase

Known as: Recombinases, Recombinases [Chemical/Ingredient] 
A broad category of enzymes that are involved in the process of GENETIC RECOMBINATION.
National Institutes of Health

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13 relations

Narrower (4)

CcrC protein, Staphylococcus aureusMerCreMer recombinaseResolvasesXerS tyrosine recombinase, Streptococcus pneumoniae R6
In BloodProcess of secretionRec A Recombinasesantagonists & inhibitors
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Broader (1)

nucleotidyltransferase

Papers overview

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Highly Cited
2007
Highly Cited
2007
Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.
Shiaoching Gong,1 Martin Doughty,1 Carroll R. Harbaugh,4 Alexander Cummins,4 Mary E. Hatten,2 Nathaniel Heintz,3 and Charles R… (More)
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Highly Cited
2004
Highly Cited
2004
Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC.
Staphylococcal cassette chromosome mec (SCCmec) is a mobile genetic element composed of the mec gene complex, which encodes… (More)
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Highly Cited
2002
Highly Cited
2002
Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer.
We have used a Prx1 limb enhancer to drive expression of Cre Recombinase in transgenic mice. This regulatory element leads to Cre… (More)
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Highly Cited
2000
Highly Cited
2000
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products.
We have developed a simple and highly efficient method to disrupt chromosomal genes in Escherichia coli in which PCR primers… (More)
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Highly Cited
2000
Highly Cited
2000
Widespread recombinase expression using FLPeR (flipper) mice.
As conditional genetic strategies advance, the need for multiple site-specific recombinase systems has emerged. To meet this need… (More)
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Highly Cited
1999
Highly Cited
1999
Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase.
Glucokinase (GK) gene mutations cause diabetes mellitus in both humans and mouse models, but the pathophysiological basis is only… (More)
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Highly Cited
1997
Highly Cited
1997
Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains.
Ligand-dependent chimeric Cre recombinases are powerful tools to induce specific DNA rearrangements in cultured cells and in mice… (More)
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Highly Cited
1997
Highly Cited
1997
Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells.
The production of subtle or conditional mutations in mice through the combined use of site-specific and homologous recombination… (More)
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Highly Cited
1989
Highly Cited
1989
The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome.
We have transferred the site-specific recombination system of the yeast 2 micron plasmid, the FLP recombinase and its… (More)
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Highly Cited
1988
Highly Cited
1988
Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.
The Cre protein encoded by the coliphage P1 is a 38-kDa protein that efficiently promotes both intra- and intermolecular synapsis… (More)
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