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recombinant human thrombopoietin

Known as: rhTPO, thrombopoietin, recombinant human, Recombinant Human TPO 
National Institutes of Health

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4 relations
THPO genecytarabine/idarubicin/recombinant human thrombopoietin

Broader (2)

ThrombopoietinThrombopoietin, human

Papers overview

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2018
2018
Predictive Value of CD4+/CD8+ Ratio in Patients with Breast Cancer Receiving Recombinant Human Thrombopoietin.
Recombinant human thrombopoietin (rhTPO) is a key determinant of therapy for chemotherapy-induced thrombocytopenia (CIT) in… 
Review
2009
Review
2009
Romiplostim: a second-generation thrombopoietin agonist.
Thrombopoietin (TPO) is the major regulator of both megakaryopoiesis and platelet production. TPO is a glycoprotein primarily… 
2008
2008
[Evaluation of recombinant human thrombopoietin in the treatment of chemotherapy-induced thrombocytopenia in lung cancer patients].
OBJECTIVE To evaluate the efficacy and safety of recombinant human thrombopoietin (rhTPO) in treatment for chemotherapy-induced… 
2002
2002
Use of thrombopoietin in combination with chemotherapy and granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization.
This phase I/II dose-escalation study examined the safety and efficacy of recombinant human thrombopoietin (rhTPO) and… 
2001
2001
Recombinant human thrombopoietin in myelosuppressive chemotherapy.
Recombinant human thrombopoietin (rhTPO) is a full-length glycosylated molecule that has been under evaluation in the setting of… 
1999
1999
Enhanced retention of in vitro functional activity of platelets from recombinant human thrombopoietin‐treated patients following long‐term cryopreservation with a platelet‐preserving solution…
Chemotherapy‐induced thrombocytopenia represents a significant clinical problem in the management of patients with malignancy… 
1997
1997
Thrombin cleaves recombinant human thrombopoietin: one of the proteolytic events that generates truncated forms of thrombopoietin.
A heterogeneity in the molecular weight (Mr) of thrombopoietin (TPO) has been reported. We found several thrombin cleavage sites… 
1997
1997
Effects of thrombopoietin (c‐mpl ligand) on growth of blast cells from patients with transient abnormal myelopoiesis and acute myeloblastic leukemia
Abstract: Thrombopoietin (TPO) is a ligand for c‐mpl that promotes both proliferation and differentiation of megakaryocytes in… 
1996
1996
The biologic properties of recombinant human thrombopoietin in the proliferation and megakaryocytic differentiation of acute myeloblastic leukemia cells.
Thrombopoietin (TPO) is implicated as a primary regulator of megakaryopoiesis and thrombopoiesis. However, the biologic effects… 
1996
1996
GpIIb/IIIa+ subpopulation of rat megakaryocyte progenitor cells exhibits high responsiveness to human thrombopoietin.
The recently cloned factor thrombopoietin (TPO) has been shown to exhibit megakaryocyte colony-stimulating activity in vitro. In… 
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