Thrombopoietin, human

Known as: MPL Ligand, TSF, Megakaryocyte Colony Stimulating Factor 
A substance made by the body that helps make blood cells, especially platelets. A form of TPO made in the laboratory is called recombinant human TPO… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Hematopoietic stem cells (HSCs) both self-renew and give rise to all blood cells for the lifetime of an individual. Xenogeneic… (More)
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Highly Cited
2009
Highly Cited
2009
Diagnosis and management of immune thrombocytopenic purpura (ITP) remain largely dependent on clinical expertise and observations… (More)
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Highly Cited
2007
Highly Cited
2007
The role of cytokines in regulation of hematopoietic stem cells (HSCs) remains poorly understood. Herein we demonstrate that… (More)
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Review
2002
Review
2002
Thrombocytopenia is a common medical problem for which the main treatment is platelet transfusion. Given the increasing use of… (More)
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Highly Cited
2000
Highly Cited
2000
The role of the chemokine binding stromal-derived factor 1 (SDF-1) in normal human megakaryopoiesis at the cellular and molecular… (More)
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Highly Cited
1998
Highly Cited
1998
Essential thrombocythaemia (ET) is a chronic myeloproliferative syndrome due to sustained proliferation of megakaryocytes, which… (More)
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Highly Cited
1997
Highly Cited
1997
Two families of small peptides that bind to the human thrombopoietin receptor and compete with the binding of the natural ligand… (More)
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Highly Cited
1996
Highly Cited
1996
Thrombopoietin (TPO), the ligand for c-mpl, stimulates proliferation of committed megakaryocytic progenitors and induces… (More)
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Highly Cited
1995
Highly Cited
1995
Thrombopoietin (c-Mpl ligand) has recently been purified and is considered to be the humoral regulator of platelet production. To… (More)
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Highly Cited
1994
Highly Cited
1994
THE major regulator of circulating platelet levels is believed to be a cytokine termed thrombopoietin1,2. It is thought to be a… (More)
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