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pyrimidine nucleotide metabolic process

Known as: pyrimidine nucleotide metabolism 
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose… 
National Institutes of Health

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Broader (2)

pyrimidine metabolic processpyrimidine metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Introduction of a Fluorine Atom at C3 of 3-Deazauridine Shifts Its Antimetabolic Activity from Inhibition of CTP Synthetase to Inhibition of Orotidylate Decarboxylase, an Early Event in the de Novo…
Background: 3-Deazauridine inhibits CTP synthetase as its 5′-triphosphate derivative and selectively depletes CTP pools. Results… 
Review
1998
Review
1998
Significance of the 5-Phosphoribosyl-1-Pyrophosphate Pool for Cardiac Purine and Pyrimidine Nucleotide Synthesis: Studies with Ribose, Adenine, Inosine, and Orotic Acid in Rats
Several experimental approaches have been applied to examine the significance of the available pool of 5-phosphoribosyl-1… 
1996
1996
Inhibitory effects of the nucleoside analogue gemcitabine on prostatic carcinoma cells
Gemcitabine (2≺,2≺difluoro‐2≺deoxycytidine, dFdC) is a synthetic antimetabolite of the cellular pyrimidine nucleotide metabolism… 
1996
1996
Purine and pyrimidine nucleotide metabolism of vascular smooth muscle cells in culture.
1986
1986
Increased sensitivity of thymidine kinase-deficient (TK-) tumor cell lines to the cell growth inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds.
Various established antiherpetic drugs, including 1-beta-D-arabinofuranosylthymine (araT), acyclovir (ACV), 9-(1,3-dihydroxy-2… 
1981
1981
In vivo rates of pyrimidine nucleotide metabolism in intact mouse T-lymphoma (s-49) cells treated with 5-fluorouracil.
Highly Cited
1980
Highly Cited
1980
Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells.
The mouse T-lymphoma (S-49) cell line is useful for individually studying RNA- and DNA-directed effects of 5-fluoropyrimidines… 
1976
1976
Enzyme pattern-directed chemotherapy: synergistic interaction of 3-deazauridine with D-galactosamine.
We tested an experimental approach in which the specialized enzymatic pattern characteristic of the tissue of origin of a tumor… 
1972
1972
[Protein synthesis in single-cell suspensions from rat liver].
1968
1968
Influence of cycloheximide (Actidione) upon pyrimidine nucleotide metabolism and rna synthesis in cocklebur leaf discs.
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