protein tyrosine phosphatase activity

Known as: PTP-phosphatase activity, tyrosylprotein phosphatase activity, PTPase activity 
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. [EC:3.1.3.48]
National Institutes of Health

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2013
2013
Substantial evidence suggests that transient production of reactive oxygen species (ROS) such as hydrogen peroxide (H(2)O(2)) is… (More)
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Highly Cited
2003
Highly Cited
2003
Zinc is an effector of insulin/IGF-1 signaling and has insulinomimetic effects, the molecular basis of which is not understood… (More)
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1999
Highly Cited
1999
Intracellular protozoan parasites of the genus Leishmania antagonize host defense mechanisms by interfering with cell signaling… (More)
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1997
1997
Signaling pathways mediated by tyrosine phosphorylation and dephosphorylation have been reported to be involved in the regulation… (More)
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1994
1994
Particulate and cytosolic protein tyrosine phosphatase (PTPase) activity was measured in skeletal muscle from 15 insulin… (More)
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1994
1994
Phosphorylation of the catalytic subunit of protein phosphatase 2A (PP2A) on threonines with a distinct autophosphorylation… (More)
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Highly Cited
1992
Highly Cited
1992
Acute (10-30 min) treatment of intact rat hepatoma (Fao) cells with H2O2, inhibits in vivo protein tyrosine phosphatase activity… (More)
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Highly Cited
1992
Highly Cited
1992
The signalling mechanism and cellular targets of the AT2 receptor are still unknown. We report that angiotensin II (Ang II… (More)
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Highly Cited
1990
Highly Cited
1990
H2O2 and vanadate are known insulinomimetic agents. Together they induce insulin's bioeffects with a potency which exceeds that… (More)
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Highly Cited
1989
Highly Cited
1989
CD45 is a family of high molecular weight leukocyte cell surface glycoproteins. Recently, two related subregions of the… (More)
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