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negative regulation of protein tyrosine phosphatase activity

Known as: negative regulation of PTP-phosphatase activity, downregulation of protein-tyrosine-phosphatase activity, down-regulation of PTP-phosphatase activity 
Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity. [GO_REF:0000059, GOC:TermGenie… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

biological control

Narrower (1)

inhibition of PPT-phosphatase activity
protein tyrosine phosphatase activity

Papers overview

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2011
2011
Down-regulation of Cytokine-induced Interleukin-8 Requires Inhibition of p38 Mitogen-activated Protein Kinase (MAPK) via MAPK Phosphatase 1-dependent and -independent Mechanisms*
Down-regulation of overabundant interleukin (IL)-8 present in cystic fibrosis (CF) airways could ease excessive neutrophil burden… 
2004
2004
Mild impairment of motor nerve repair in mice lacking PTP-BL tyrosine phosphatase activity.
Mouse PTP-BL is a large, nontransmembrane protein tyrosine phosphatase of unclear physiological function that consists of a KIND… 
2002
2002
Low M r Phosphotyrosine Protein Phosphatase Associates and Dephosphorylates p125 Focal Adhesion Kinase, Interfering with Cell Motility and Spreading*
Low M r phosphotyrosine protein phosphatase interferes in vivo with the activation of several growth factor receptors and is… 
2001
2001
Altered Regulation of ERK1b by MEK1 and PTP-SL and Modified Elk1 Phosphorylation by ERK1b Are Caused by Abrogation of the Regulatory C-terminal Sequence of ERKs*
ERK1b is an alternatively spliced form of ERK1, containing a 26-amino acid insertion between residues 340 and 341 of ERK1… 
Highly Cited
2000
Highly Cited
2000
Effects of Src Homology Domain 2 (SH2)-Containing Inositol Phosphatase (SHIP), SH2-Containing Phosphotyrosine Phosphatase (SHP)-1, and SHP-2 SH2 Decoy Proteins on FcγRIIB1-Effector Interactions and…
Coaggregation of FcγRIIB1 with B cell Ag receptors (BCR) leads to inhibition of BCR-mediated signaling via recruitment of Src… 
2000
2000
LMW-PTP exerts a differential regulation on PDGF- and insulin-mediated signaling.
Low-molecular-weight protein tyrosine phosphatase (LMW-PTP) is able to specifically bind and dephosphorylate activated PDGF and… 
Highly Cited
1993
Highly Cited
1993
Tyrosine kinases and phosphoinositide metabolism in thrombin-stimulated human platelets.
In this study we have examined the implication of tyrosine kinase activities in aggregation, 5-hydroxytryptamine secretion and… 
Highly Cited
1992
Highly Cited
1992
The dephosphorylation of insulin and epidermal growth factor receptors. Role of endosome-associated phosphotyrosine phosphatase(s).
Highly Cited
1980
Highly Cited
1980
Purification and subunit structure of a high-molecular-weight phosphoprotein phosphatase (phosphatase II) from rat liver.
1. Phosphatase II is a form of phosphoprotein phosphatase originally found in rat liver extract; it has a molecular weight of 160… 
1959
1959
The Marine Biological Association of India
It is established experimentally that the inshore areas of the Gulf of Mannar and Palk Bay bordering Mandapam Camp can profitably… 
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