protein import into nucleus

Nearly 20 years after its identification as a new β-karyopherin mediating the nuclear import of the RNA-binding protein hnRNP A1… Expand

Within a single generation time a growing yeast cell imports ∼14 million ribosomal proteins (r-proteins) into the nucleus for… Expand

Snail, a zinc finger-containing transcriptional regulator, migrates into the nucleus where it controls gene expression. We… Expand

Intracellular transport of karyophilic cargos comprises translocation to the nuclear envelope and subsequent nuclear import… Expand

Green fluorescent protein-based reporters are commonly used to investigate protein nucleocytoplasmic transport. In this study we… Expand

BackgroundNuclear import of proteins is typically mediated by their physical interaction with soluble cytosolic receptor proteins… Expand

Transport of the viral genome into the nucleus required phosphorylation of components in the preintegration complex by virion… Expand

We have developed a simple genetic assay to detect active nuclear localization (NLS) and export signals (NES) on the basis of… Expand

Protein nuclear import factors are not, in general, believed to function in the nuclear export of macromolecules and their… Expand

In this chapter we have presented the most recent methods for the preparation of cell extracts and recombinant protein factors… Expand