N. Zhang

Publications378
h-index42
Citations7,936
Highly Influential Citations302
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Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle
Since the discovery of γ-tubulin, attention has focused on its involvement as a microtubule nucleator at the centrosome. However, mislocalization of γ-tubulin away from the centrosome does not… Expand
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Circulating histones are mediators of trauma-associated lung injury.
RATIONALE Acute lung injury is a common complication after severe trauma, which predisposes patients to multiple organ failure. This syndrome largely accounts for the late mortality that arises and… Expand
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Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease.
BACKGROUND Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by the accumulation of inflammatory cells; however, an eosinophil predominance is seen in white (Belgian), but not Asian… Expand
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Environmental efficiency analysis of transportation system in China:A non-radial DEA approach
Many countries are worried about reducing energy consumption and environmental pollution while increasing the productivity and efficiency of their industries. This study intends to contribute to the… Expand
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Role of staphylococcal superantigens in upper airway disease
Purpose of reviewChronic rhinosinusitis with nasal polyps often represents a chronic severe inflammatory disease of the upper airways and may serve as a model for lower airway diseases such as… Expand
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Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma.
BACKGROUND Nasal polyps often are associated with asthma. The phenotype of these patients is unknown. OBJECTIVE To identify the mucosal factors associated with asthma comorbidity, we analyzed the… Expand
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Extended Outbreak of Cryptosporidiosis in a Pediatric Hospital, China
Four Cryptosporidium spp. and 6 C. hominis subtypes were isolated from 102 of 6,284 patients in 3 pediatric hospitals in People’s Republic of China. A cryptosporidiosis outbreak was identified… Expand
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Pathogenesis of chronic rhinosinusitis: inflammation.
Chronic rhinosinusitis (CRS) is a heterogeneous group of inflammatory diseases of the nasal and paranasal cavities either accompanied by polyp formation (CRSwNP) or without polyps (CRSsNP). CRSsNP… Expand
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In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.
Recombinant methioninase (rMETase) is an enzyme active in preclinical mouse models of human cancer. The efficacy of rMETase is due to depletion of plasma methionine, an amino acid for which tumors… Expand
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mdmx is a negative regulator of p53 activity in vivo.
Regulation of p53 protein activity is required for normal embryogenesis, tumor suppression, and cellular response to DNA damage. Here we report that loss of mdmx, a p53-binding protein, results in… Expand
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