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protein-glutamine:amine gamma-glutamyltransferase activity

Known as: protein-glutamine gamma-glutamyltransferase activity, fibrinoligase activity, glutaminylpeptide gamma-glutamyltransferase activity 
Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
We have found that tissue-type transglutaminase (tTG), also called TGc, TGase2 and Galpha(h), has the activity of protein… Expand
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Highly Cited
2002
Highly Cited
2002
The precise cause of neuronal death in Huntington's disease (HD) is unknown. Proteolytic products of the huntingtin protein can… Expand
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Review
2000
Review
2000
Tissue transglutaminase is a multifunctional protein that is likely to play a role in numerous processes in the nervous system… Expand
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Highly Cited
1999
Highly Cited
1999
The polyglutamine-expanded N-terminal region of mutant huntingtin causes neurodegeneration in Huntington's disease (HD). Neuronal… Expand
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Highly Cited
1997
Highly Cited
1997
Transglutaminase is a calcium-activated enzyme that crosslinks substrate proteins into insoluble, often filamentous aggregates… Expand
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Highly Cited
1994
Highly Cited
1994
The alpha 1-adrenergic receptors activate a phospholipase C enzyme by coupling to members of the large molecular size… Expand
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Highly Cited
1991
Highly Cited
1991
The laminin-nidogen complex, a major component of basement membranes, incorporates [3H]putrescine and monodansylcadaverine in the… Expand
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Highly Cited
1987
Highly Cited
1987
During the involution of lead nitrate‐induced hyperplasia in rat liver a significant increase of transglutaminase activity… Expand
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Highly Cited
1987
Highly Cited
1987
Guanosine 5'-triphosphate (GTP) was found to inhibit guinea pig liver transglutaminase activity as measured by [3H]putrescine… Expand
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Highly Cited
1985
Highly Cited
1985
By use of a radiometric assay transglutaminase activity was demonstrated for the first time in human jejunal mucosa. The activity… Expand
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