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protein-glutamine:amine gamma-glutamyltransferase activity

Known as: protein-glutamine gamma-glutamyltransferase activity, fibrinoligase activity, glutaminylpeptide gamma-glutamyltransferase activity 
Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Transglutaminases

Broader (1)

cornified envelope assembly

Narrower (1)

tissue transglutaminase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
A novel function of tissue-type transglutaminase: protein disulphide isomerase.
We have found that tissue-type transglutaminase (tTG), also called TGc, TGase2 and Galpha(h), has the activity of protein… Expand
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Highly Cited
2002
Highly Cited
2002
Therapeutic Effects of Cystamine in a Murine Model of Huntington's Disease
The precise cause of neuronal death in Huntington's disease (HD) is unknown. Proteolytic products of the huntingtin protein can… Expand
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Review
2000
Review
2000
Tissue transglutaminase: a possible role in neurodegenerative diseases
Tissue transglutaminase is a multifunctional protein that is likely to play a role in numerous processes in the nervous system… Expand
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Highly Cited
1999
Highly Cited
1999
Tissue transglutaminase is increased in Huntington's disease brain.
The polyglutamine-expanded N-terminal region of mutant huntingtin causes neurodegeneration in Huntington's disease (HD). Neuronal… Expand
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Highly Cited
1997
Highly Cited
1997
Transglutaminase activity is increased in Alzheimer's disease brain
Transglutaminase is a calcium-activated enzyme that crosslinks substrate proteins into insoluble, often filamentous aggregates… Expand
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Highly Cited
1994
Highly Cited
1994
Gh: a GTP-binding protein with transglutaminase activity and receptor signaling function.
The alpha 1-adrenergic receptors activate a phospholipase C enzyme by coupling to members of the large molecular size… Expand
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Highly Cited
1991
Highly Cited
1991
Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.
The laminin-nidogen complex, a major component of basement membranes, incorporates [3H]putrescine and monodansylcadaverine in the… Expand
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Highly Cited
1987
Highly Cited
1987
Induction and activation of tissue transglutaminase during programmed cell death
During the involution of lead nitrate‐induced hyperplasia in rat liver a significant increase of transglutaminase activity… Expand
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Highly Cited
1987
Highly Cited
1987
Identification of a guanosine triphosphate-binding site on guinea pig liver transglutaminase. Role of GTP and calcium ions in modulating activity.
Guanosine 5'-triphosphate (GTP) was found to inhibit guinea pig liver transglutaminase activity as measured by [3H]putrescine… Expand
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Highly Cited
1985
Highly Cited
1985
Human jejunal transglutaminase: demonstration of activity, enzyme kinetics and substrate specificity with special relation to gliadin and coeliac disease.
By use of a radiometric assay transglutaminase activity was demonstrated for the first time in human jejunal mucosa. The activity… Expand
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