protein-glutamine:amine gamma-glutamyltransferase activity

Known as: protein-glutamine gamma-glutamyltransferase activity, fibrinoligase activity, glutaminylpeptide gamma-glutamyltransferase activity 
Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl… (More)
National Institutes of Health

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2 relations
Transglutaminases

Broader (1)

cornified envelope assembly

Papers overview

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Review
2005
Review
2005
Future therapeutic options for celiac disease
Celiac disease is a disorder of the small intestine caused by an inappropriate immune response to wheat gluten and similar… (More)
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Highly Cited
2003
Highly Cited
2003
A novel function of tissue-type transglutaminase: protein disulphide isomerase.
We have found that tissue-type transglutaminase (tTG), also called TGc, TGase2 and Galpha(h), has the activity of protein… (More)
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Highly Cited
2003
Highly Cited
2003
Tissue transglutaminase mediates activation of RhoA and MAP kinase pathways during retinoic acid-induced neuronal differentiation of SH-SY5Y cells.
All-trans-retinoic acid (RA) plays a crucial role in survival and differentiation of neurons. For elucidating signaling… (More)
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Highly Cited
2002
Highly Cited
2002
Therapeutic effects of cystamine in a murine model of Huntington's disease.
The precise cause of neuronal death in Huntington's disease (HD) is unknown. Proteolytic products of the huntingtin protein can… (More)
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Highly Cited
1998
Highly Cited
1998
Distinct nuclear localization and activity of tissue transglutaminase.
Tissue transglutaminase is a calcium-dependent transamidating enzyme that has been postulated to play a role in the pathology of… (More)
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Highly Cited
1994
Highly Cited
1994
Gh: a GTP-binding protein with transglutaminase activity and receptor signaling function.
The alpha 1-adrenergic receptors activate a phospholipase C enzyme by coupling to members of the large molecular size… (More)
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Highly Cited
1991
Highly Cited
1991
Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.
The laminin-nidogen complex, a major component of basement membranes, incorporates [3H]putrescine and monodansylcadaverine in the… (More)
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Highly Cited
1987
Highly Cited
1987
Induction and activation of tissue transglutaminase during programmed cell death.
During the involution of lead nitrate-induced hyperplasia in rat liver a significant increase of transglutaminase activity… (More)
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Highly Cited
1987
Highly Cited
1987
Identification of a guanosine triphosphate-binding site on guinea pig liver transglutaminase. Role of GTP and calcium ions in modulating activity.
Guanosine 5'-triphosphate (GTP) was found to inhibit guinea pig liver transglutaminase activity as measured by [3H]putrescine… (More)
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Highly Cited
1982
Highly Cited
1982
Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Mouse epidermal basal cells can be selectively cultivated in medium with 0.02 to 0.09 mM Ca2+ and can be induced to differentiate… (More)
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