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Calcium regulation of growth and differentiation of mouse epidermal cells in culture
Modification of the ionic calcium concentration in the culture medium markedly alters the pattern of proliferation and differentiation in cultured mouse epidermal cells. When medium calcium isExpand
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Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro
Epidermal differentiation is characterized by a series of coordinated morphological and biochemical changes which result in a highly specialized, highly organized, stratified squamous epithelium.Expand
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Differential Expression of Multiple Transglutaminases in Human Brain
The transglutaminase (TGase) family of enzymes, of which seven different members are known in the human genome, participate in many biological processes involving cross-linking proteins into largeExpand
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Molecular and cellular biology of intermediate filaments.
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Bricks and mortar of the epidermal barrier
A specialized tissue type, the keratinizing epithelium, protects terrestrial mammals from water loss and noxious physical, chemical and mechanical insults. This barrier between the body and theExpand
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Intermediate filaments
Intermediate filaments form a class of insoluble cytoplasmic filaments ofdimensions intermediate in size between those of microtubules (about 25 nm in diameter) and microfilaments (about 7 nm inExpand
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The Proteins Elafin, Filaggrin, Keratin Intermediate Filaments, Loricrin, and Small Proline-rich Proteins 1 and 2 Are Isodipeptide Cross-linked Components of the Human Epidermal Cornified Cell
The cornified cell envelope (CE) is a 15-nm thick layer of insoluble protein deposited on the intracellular side of the cell membrane of terminally differentiated stratified squamous epithelia. TheExpand
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Epithelial barrier function: assembly and structural features of the cornified cell envelope.
Terminally differentiating stratified squamous epithelial cells assemble a specialized protective barrier structure on their periphery termed the cornified cell envelope (CE). It is composed ofExpand
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Direct Evidence That Involucrin Is a Major Early Isopeptide Cross-linked Component of the Keratinocyte Cornified Cell Envelope*
Involucrin was the first protein to be identified as a likely constituent of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. However, to date, direct isolation from CEsExpand
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Assembly of the epidermal cornified cell envelope.
The cornified cell envelope structure is formed beneath the plasma membrane in terminally differentiating stratified squamous epithelia. It provides a vital physical barrier to these tissues inExpand
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