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prostaglandin-endoperoxide synthase activity

Known as: fatty acid cyclooxygenase activity, (PG)H synthase activity, prostaglandin synthase activity 
Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. [EC:1.14.99.1]
National Institutes of Health

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2 relations
Prostaglandin-Endoperoxide Synthasecyclooxygenase 1

Papers overview

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1986
1986
7-Aroyl-2,3-dihydrobenzo[b]furan-3-carboxylic acids and 7-benzoyl-2,3-dihydrobenzo[b]thiophene-3-carboxylic acids as analgesic agents.
The synthesis of a series of 7-aroyl-2,3-dihydrobenzo[b]furan-3-carboxylic acids and 7-benzoyl-2,3-dihydrobenzo[b]thiophene-3… 
1980
1980
Regulation of prostaglandin synthesis during differentiation of cultured mouse myeloid leukemia cells
Mouse myeloid leukemia cells (Ml) were induced to differentiate into mature macrophages and granulocytes by various inducers. The… 
1979
1979
Prostaglandin synthetase and prostaglandin E2 levels in human breast carcinoma.
Highly Cited
1977
Highly Cited
1977
Effects of exogenous progesterone and oestradiol on prostaglandin F and 13,14-dihydro-15-oxo prostaglandin F2alpha concentrations in uteri and plasma of ovariectomized ewes.
The effects of progesterone and estradiol administration on plasma and uterine concentrations of prostaglandin F2alpha (PGF2a… 
Highly Cited
1977
Highly Cited
1977
Prostaglandin metabolism in the kidneys of spontaneously hypertensive rats.
Renal prostaglandins have been implicated in the regulation of blood pressure. We have therefore compared prostaglandin… 
1977
1977
Comparison of effects of aspirin and indomethacin on human platelet prostaglandin synthetase.
Human platelets were incubated in vitro with either aspirin or indomethacin and the prostaglandin synthetase activity of the… 
1976
1976
The effect of anti-inflammatory agents on human synovial fibroblast prostaglandin synthetase.
Highly Cited
1975
Highly Cited
1975
On agents favoring prostaglandin f formation during biosynthesis.
The microsomal fraction of bovine vesicular gland catalyzed the conversion of eicosapolyenoic acids exclusively to prostaglandin… 
Highly Cited
1973
Highly Cited
1973
Radioimmunological assay of prostaglandin synthetase activity.
Highly Cited
1972
Highly Cited
1972
Prostaglandin synthetase activity in the rat stomach fundus. Activation by L-norepinephrine and related compounds.
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