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proguanil hydrochloride

Known as: Imidodicarbonimidic Diamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-, Monohydrochloride(9CI), Hydrochloride, Proguanil, Bigumalum 
The hydrochloride salt form of proguanil, a synthetic biguanide derivative of pyrimidine and an folate antagonist with antimalarial property. Upon… 
National Institutes of Health

Related topics

Related topics

5 relations
Atovaquone 250 MG / proguanil hydrochloride 100 MG Oral TabletAtovaquone 62.5 MG / proguanil hydrochloride 25 MG Oral Tablet [Malarone]Proguanil

Narrower (2)

MalaronePaludrine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Tolérance et efficacité de l’atovaquone-proguanil dans le traitement du paludisme d’importation à Plasmodium falciparum de l’enfant en France métropolitaine : expérience d’un centre hospitalier…
2006
2006
Les résistances aux médicaments antipaludiques
2002
2002
Dual-mode gradient HPLC procedure for the simultaneous determination of chloroquine and proguanil.
Review
1999
Review
1999
Atovaquone and proguanil hydrochloride for treatment of malaria.
BACKGROUND Safe and effective new drugs are needed for treatment of malaria. Atovaquone and proguanil hydrochloride is a new… 
1999
1999
Evaluation of the H-point standard additions method (HPSAM) and the generalized H-point standard additions method (GHPSAM) for the UV-analysis of two-component mixtures.
1995
1995
Determination of proguanil and metabolites in small sample volumes of whole blood stored on filter paper by high-performance liquid chromatography.
Highly Cited
1988
Highly Cited
1988
Comparison of mosquito nets, proguanil hydrochloride, and placebo to prevent malaria.
One hundred and ninety students aged 6 to 18 at a boarding school 120 km west of Nairobi in the Rift Valley participated in a… 
1988
1988
Steady-state kinetics of proguanil and its active metabolite, cycloguanil, in man.
The pharmacokinetics of proguanil and its active metabolite, cycloguanil, were determined at steady-state in 6 healthy male… 
1970
1970
Treatment of falciparum malaria caused by strain resistant to quinine.
Malaria caused by the Vietnam (Smith) strain of Plasmodium falciparum, isolated from a patient in the United States in 1969, is… 
1965
1965
Preliminary evaluation of cycloguanil pamoate in dermal leishmaniasis.
SOME REGRESSION of early lesions of dermal leishmaniasis has been observed by one of the authors (A.P.C.) in malaria patients… 
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