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Proguanil

Known as: Imidodicarbonimidic diamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-, Chlorguanid, Proguanilum 
A biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.
National Institutes of Health

Related topics

Related topics

25 relations

Broader (2)

AntimalarialsAntimetabolites

Narrower (10)

Atovaquone / ProguanilBigumalChloriguaneMalarone
Atovaquone 250 MG / proguanil hydrochloride 100 MG Oral TabletAtovaquone 62.5 MG / proguanil hydrochloride 25 MG Oral Tablet [Malarone]Drug AllergyIn Blood

Papers overview

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2004
2004
IS 17α-ETHINYL ESTRADIOL AN INHIBITOR OF CYTOCHROME P450 2C19?
We have read with great interest the increasing number of publications reporting that oral contraceptive (OC)[1][1] formulations… 
1998
1998
Acute generalized exanthematous pustulosis due to the combination of chloroquine and proguanil.
The association of chloroquine and proguanil is widely used for antimalarial prophylaxis in Plasmodium falciparum – endemic… 
1968
1968
Monkey to man transmission of Plasmodium falciparum by Anopheles freeborni mosquitoes.
Infections of Plasmodium falciparum (Malayan IV strain) in the Aotus trivirgatus monkey were shown to be infectious to Anopheles… 
1965
1965
The effect of cycloguanil pamoate (CI-501) against a chlorguanide-resistant Chesson strain of Plasmodium vivax.
1964
1964
THE ANTIMALARIAL ACTIVITY OF CI-501 (CAMOLAR) AGAINST FALCIPARUM MALARIA.
Summary A repository preparation of the dihydrotriazine metabolite of chlorguanide, known as CI-501 (Camolar®), given as a single… 
1964
1964
STUDIES ON A STRAIN OF CHLOROQUINE-RESISTANT PLASMODIUM FALCIPARUM FROM THAILAND.
Infections with a strain of Plasmodium falciparum from Thailand, termed the Thailand (JHK) strain, were established in 25 non… 
1963
1963
THE EFFECT OF A REPOSITORY PREPARATION OF THE DIHYDROTRIAZINE METABOLITE OF CHLORGUANIDE, CI-501, AGAINST THE CHESSON STRAIN OF PLASMODIUM VIVAX IN MAN.
Summary A repository preparation of the dihydrotriazine metabolite of chlorguanide, CI-501, was tested in 28 volunteers for its… 
1951
1951
A 2 : 4-Diamino Pyrimidine in the Treatment of Proguanil-resistant Laboratory Malarial Strains
A SERIES of 2 : 4-diamino pyrimidines substituted in the 5- and/or 6-position has recently been described1 as having activity… 
1950
1950
Cross-resistance between sulphanilamide and paludrine (proguanil) in a strain of Plasmodium gallinaceum resistant to sulphanilamide
1. Resistance to sulphanilamide, of a low order, has been developed in a strain of Plasmodium gallinaceum by the treatment of… 
1948
1948
On the ability of Plasmodium lophurae to acquire resistance to chlorguanide, camoquin and chloroquine.