Proguanil

Known as: Imidodicarbonimidic diamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-, Chlorguanid, Proguanilum

A biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.

National Institutes of Health

Papers overview

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1989

The effects of three separate antimalarial prophylactic regimens (proguanil, sulfisoxazole, and proguanil plus sulfisoxazole) and…

1970

Among the more promising groups of drugs undergoing evaluation as antimalarial agents are the folic acid antagonists. These…

1967

OVER a billion people live in tropical and subtropical areas where malaria is still a serious threat. 1,2 The global eradication…

1965

1964

Summary A repository preparation of the dihydrotriazine metabolite of chlorguanide, known as CI-501 (Camolar®), given as a single…

1963

Summary A repository preparation of the dihydrotriazine metabolite of chlorguanide, CI-501, was tested in 28 volunteers for its…

1952

Summary The activities of the triazine metabolites of chlorguanide and dichlorguanide have been studied in P. cynomolgi…

1951

A SERIES of 2 : 4-diamino pyrimidines substituted in the 5- and/or 6-position has recently been described1 as having activity…

1950

Only in details do we diverge. My older cases, contrary to Keynes's general assessment, have done fully as well as the cases of…

1948