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The evolution of primate malaria parasites based on the gene encoding cytochrome b from the linear mitochondrial genome.
We report a phylogenetic analysis of primate malaria parasites based on the gene encoding the cytochrome b protein from the mitochondrial genome. We have studied 17 species of Plasmodium, includingExpand
A monkey's tale: the origin of Plasmodium vivax as a human malaria parasite.
The high prevalence of Duffy negativity (lack of the Duffy blood group antigen) among human populations in sub-Saharan Africa has been used to argue that Plasmodium vivax originated on thatExpand
Genetic selection of a Plasmodium-refractory strain of the malaria vector Anopheles gambiae.
The anopheline mosquito is the target in most malaria control programs, primarily through the use of residual insecticides. A mosquito was studied that is refractory to most species of malariaExpand
Plasmodium ovale: Parasite and Disease
SUMMARY Humans are infected by four recognized species of malaria parasites. The last of these to be recognized and described is Plasmodium ovale. Like the other malaria parasites of primates, thisExpand
Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes.
While anaemia has long been recognized as a consequence of acute infections with malaria, the relative contributions of direct erythrocyte destruction by parasites, destruction of uninfectedExpand
Genesis, sequestration and survival of Plasmodium falciparum gametocytes: parameter estimates from fitting a model to malariatherapy data.
Plasmodium falciparum malaria is one of mankind's main killers. Part of the parasite's life-cycle is spent in human blood, mainly as asexual stages. A fraction of the asexual parasites develops intoExpand
Plasmodium malariae: Parasite and Disease
SUMMARY A review of the life history of Plasmodium malariae, the quartan malaria parasite of humans, is presented. Much of the information is based on data obtained from induced infections in humansExpand
Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax.
The population structure of Plasmodium vivax remains elusive. The markers of choice for large-scale population genetic studies of eukaryotes, short tandem repeats known as microsatellites, have beenExpand
Circumsporozoite proteins of human malaria parasites Plasmodium falciparum and Plasmodium vivax
Monoclonal antibodies were raised against sporozoites of two species of malaria parasites, Plasmodium falciparum and Plasmodium vivax. The antibodies reacted with polypeptides (circumsporozoiteExpand
A Systems-Based Analysis of Plasmodium vivax Lifecycle Transcription from Human to Mosquito
Background Up to 40% of the world's population is at risk for Plasmodium vivax malaria, a disease that imposes a major public health and economic burden on endemic countries. Because P. vivaxExpand