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polynucleotide 5'-hydroxyl-kinase activity

Known as: polynucleotide 5'-hydroxyl kinase (phosphorylating) activity, 5'-hydroxyl polynucleotide kinase activity, polynucleotide 5'-hydroxy-kinase activity 
Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. [EC:2.7.1.78]
National Institutes of Health

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polynucleotide kinase activity

Papers overview

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Highly Cited
2018
Highly Cited
2018
A Dual-Enzyme-Assisted Three-Dimensional DNA Walking Machine Using T4 Polynucleotide Kinase as Activators and Application in Polynucleotide Kinase Assays.
T4 polynucleotide kinase (T4 PNK), an intracellular kinase, catalyzes the phosphorylation of 5'-hydroxyl termini in nucleic acids… 
Highly Cited
2015
Highly Cited
2015
A highly sensitive electrochemiluminescence assay for protein kinase based on double-quenching of graphene quantum dots by G-quadruplex-hemin and gold nanoparticles.
2015
2015
Detection of T4 polynucleotide kinase activity based on cationic conjugated polymer-mediated fluorescence resonance energy transfer.
2015
2015
Label-free and sensitive detection of T4 polynucleotide kinase activity via coupling DNA strand displacement reaction with enzymatic-aided amplification.
Highly Cited
2014
Highly Cited
2014
Label-free luminescence switch-on detection of T4 polynucleotide kinase activity using a G-quadruplex-selective probe.
A label-free, oligonucleotide-based, switch-on luminescence detection method for T4 polynucleotide kinase activity has been… 
2014
2014
Amplified electrochemical detection of protein kinase activity based on gold nanoparticles/multi-walled carbon nanotubes nanohybrids.
2010
2010
Highly sensitive detection of DNA phosphorylation by counting single nanoparticles
AbstractDNA phosphorylation is a vital process in the repair, replication, and recombination of nucleic acids. Traditionally, it… 
Highly Cited
2009
Highly Cited
2009
DNA 3′-Phosphatase Activity Is Critical for Rapid Global Rates of Single-Strand Break Repair following Oxidative Stress
ABSTRACT Oxidative stress is a major source of chromosome single-strand breaks (SSBs), and the repair of these lesions is… 
Highly Cited
2009
Highly Cited
2009
Photoaffinity labeling reveals nuclear proteins that uniquely recognize cisplatin-DNA interstrand cross-links.
The DNA-binding inorganic compound cisplatin is one of the most successful anticancer drugs. The detailed mechanism by which… 
Highly Cited
2005
Highly Cited
2005
Real-time investigation of nucleic acids phosphorylation process using molecular beacons
Phosphorylation of nucleic acids is an indispensable process to repair strand interruption of nucleic acids. We have studied the… 
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