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pitavastatin

Known as: Pitavastatia, (3R,5S,6E)-7-[2-Cyclopropyl-4-(P-Fluorophenyl)-3-Quinolyl]-3,5-Dihydroxy-6-Heptenoic Acid, Pitavastatinum 
A novel statin that induces plaque regression and elevates HDL-cholesterol levels.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Hydroxymethylglutaryl-CoA Reductase InhibitorsQuinolines

Narrower (3)

LivaloNK 104pitavastatin calcium
pitavastatin 4 MG Oral Tablet [Livalo]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Pitavastatin inhibits hepatic steatosis and fibrosis in non‐alcoholic steatohepatitis model rats
Aim:  Non‐alcoholic steatohepatitis (NASH) may progress to liver cirrhosis, and NASH patients with liver cirrhosis are at risk of… 
2010
2010
OATP1B1 388A>G polymorphism and pharmacokinetics of pitavastatin in Chinese healthy volunteers
Purpose:  To investigate the contribution of the most frequent single nucleotide polymorphism (SNPs) of the organic anion… 
2010
2010
Pitavastatin reduces oxidative stress and attenuates intermittent hypoxia-induced left ventricular remodeling in lean mice
We have reported previously that intermittent hypoxia related to sleep apnea induces cardiovascular remodeling secondary to the… 
2009
2009
Effects of acid and lactone forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on the induction of MDR1 expression and function in LS180 cells.
Highly Cited
2008
Highly Cited
2008
Rapid Stabilization of Vulnerable Carotid Plaque Within 1 Month of Pitavastatin Treatment in Patients With Acute Coronary Syndrome
We determined time course of stabilization of echolucent carotid plaques by statin therapy in patients with acute coronary… 
2008
2008
Determination of two HMG-CoA reductase inhibitors, pravastatin and pitavastatin, in plasma samples using liquid chromatography-tandem mass spectrometry for pharmaceutical study.
We developed a method for determining pravastatin or pitavastatin, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase… 
Highly Cited
2005
Highly Cited
2005
Statin attenuates high glucose-induced and diabetes-induced oxidative stress in vitro and in vivo evaluated by electron spin resonance measurement.
2003
2003
Uptake mechanism of pitavastatin, a new inhibitor of HMG-CoA reductase, in rat hepatocytes.
To understand the mechanism underlying the highly liver-selective distribution of pitavastatin, uptake experiments were performed… 
Highly Cited
2002
Highly Cited
2002
HMG-CoA reductase inhibitor decreases small dense low-density lipoprotein and remnant-like particle cholesterol in patients with type-2 diabetes.
Review
2002
Review
2002
Managing dyslipidemia in the high-risk patient.
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