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piperidine-4-sulfonic acid

Known as: 4-Piperidinesulfonic acid, piperidine-4-sulphonic acid 
National Institutes of Health

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2 relations

Broader (2)

GABA AgonistsPiperidines

Papers overview

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Highly Cited
2006
Highly Cited
2006
Pharmacological Characterization of Agonists at δ-Containing GABAA Receptors: Functional Selectivity for Extrasynaptic Receptors Is Dependent on the Absence of γ2
Several groups have characterized the pharmacology of α4- or α6β3δ-containing GABAA receptors expressed in different cell systems… 
Highly Cited
2004
Highly Cited
2004
Activation of single heteromeric GABAA receptor ion channels by full and partial agonists
The linkage between agonist binding and the activation of a GABAA receptor ion channel is yet to be resolved. This aspect was… 
2000
2000
Allosteric modulators affect the efficacy of partial agonists for recombinant GABAA receptors
Different α subunits of human γ‐aminobutyric acid type A (GABAA) receptors were transiently expressed together with β3 and γ2… 
Highly Cited
1999
Highly Cited
1999
Mutation at the putative GABAA ion‐channel gate reveals changes in allosteric modulation
We have mutated a conserved leucine in the putative membrane‐spanning domain to serine in human GABAA β2 and investigated the… 
Highly Cited
1996
Highly Cited
1996
Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha 4 subunit.
The alpha subunits are an important determinant of the pharmacology of gamma-aminobutyric acidA (GABAA) receptors with respect to… 
Highly Cited
1990
Highly Cited
1990
Characterization of gabaergic seizure regulation in the midline thalamus
Highly Cited
1990
Highly Cited
1990
The central medial nucleus: thalamic site of seizure regulation
1985
1985
GABA‐Mimetic Activity and Effects on Diazepam Binding of Aminosulphonic Acids Structurally Related to Piperidine‐4‐Sulphonic Acid
The relationship between structure, in vivo activity, and in vitro activity of some analogues of the γ‐aminobutyric acid (GABA… 
Highly Cited
1982
Highly Cited
1982
Differences between GABA receptor binding to membranes from cerebellum during postnatal development and from cultured cerebellar granule cells.
GABA receptor binding sites were determined in membranes from cerebella of 7-, 15- and 60-day-old rats and cerebellar granule… 
Review
1979
Review
1979
Partial agonists for brain GABA/benzodiazepine receptor complex
BENZODIAZEPINE receptors in the brain1 are activated by γ-aminobutyric acid (GABA) and by the GABA agonist muscimol in vitro2… 
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