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physostigmine heptyl

Known as: Eptastigmine, heptylphysostigmine, heptyl-physostigmine 
National Institutes of Health

Related topics

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4 relations

Broader (2)

Cholinesterase InhibitorsPhysostigmine

Narrower (1)

MF 201
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Efficacy and safety of eptastigmine for the treatment of patients with Alzheimer’s disease
Objective: To evaluate the efficacy and safety of eptastigmine in patients with moderate to moderately severe AD. Background… 
Highly Cited
1999
Highly Cited
1999
Success of pyridostigmine, physostigmine, eptastigmine and phosphotriesterase treatments in acute sarin intoxication.
1999
1999
Two-Year Treatment of Alzheimer’s Disease with Eptastigmine
The effectiveness of long-term treatment of Alzheimer’s disease with cholinesterase inhibitors is a matter of controversy. We… 
1998
1998
Maximum Tolerated Dose and Pharmacodynamics of Eptastigmine in Elderly Healthy Volunteers
Eptastigmine is a new acetylcholinesterase (AChE) inhibitor currently under development for the symptomatic treatment of… 
1998
1998
A 25-week placebo-controlled study of eptastigmine in patients with Alzheimer disease.
The efficacy and safety of eptastigmine in patients with probable Alzheimer disease was evaluated in a double-blind, placebo… 
1994
1994
A Pharmacodynamic Strategy to Optimize the Clinical Response to Eptastigmine (MF-201)
Clinical results obtained over the past 20 years with acetylcholinesterase (AChE) inhibitors in Alzheimer’s disease (AD) have… 
1993
1993
Cholinesterase inhibitor effects on extracellular acetylcholine in rat cortex
1993
1993
Prolonged Effects of Cholinesterase Inhibition with Eptastigmine on the Cerebral Blood Flow-Metabolism Ratio of Normal Rats
The cerebrovascular and metabolic effects of the novel cholinesterase inhibitor eptastigmine were tested in conscious rats. The… 
1992
1992
Heptyl‐physostigmine enhances basal forebrain control of cortical cerebral blood flow
This study sought to determine the effect of heptylphysostigmine (H‐PHY), a reversible cholinesterase (ChE) inhibitor with… 
1989
1989
The effect of heptyl-physostigmine, a new cholinesterase inhibitor, on the central cholinergic system of the rat
Heptyl-physostigmine (Heptyl-Phy; MF-201) is a new carbamate derivative of physostigmine (Phy) with greater lipophilicity and… 
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