Skip to search formSkip to main contentSkip to account menu

phenylalanine-tRNA ligase activity

Known as: phenylalanyl-transfer RNA ligase activity, phenylalanyl-tRNA ligase activity, L-phenylalanyl-tRNA synthetase activity 
Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). [EC:6.1.1.20]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1988
1988
Ribosomal binding and dipeptide formation by misacylated tRNA(Phe),S.
Eight structurally modified peptidyl-tRNA(Phe),s were employed to study P-site binding and peptide bond formation in a cell-free… 
Highly Cited
1984
Highly Cited
1984
tRNA binding sites of ribosomes from Escherichia coli.
70S tight-couple ribosomes from Escherichia coli were studied with respect to activity and number of tRNA binding sites. The… 
Highly Cited
1983
Highly Cited
1983
Binding of yeast tRNAPhe anticodon arm to Escherichia coli 30 S ribosomes.
1981
1981
The role of spermine in preventing misacylation by phenylalanyl-tRNA synthetase.
1980
1980
Amino acid substitutions in protein biosynthesis. Poly(A)-directed polyphenylalanine synthesis.
The fidelity of protein biosynthesis in vitro was studied quantitatively in a well defined system that employed poly(A) as a… 
Highly Cited
1976
Highly Cited
1976
Regions of tRNA important for binding to the ribosomal A and P sites.
Studies on the enzymatic inhibition of phenylalanyl-tRNAPhe and formylmethionyl-tRNAFMet binding to the ribosomes by defined tRNA… 
Highly Cited
1974
Highly Cited
1974
Proteins at the tRNA binding sites of Escherichia coli ribosomes.
p - Nitrophenylcarbamyl - phenylalanyl-tRNA binds to ribosomes in response to poly(U) and reacts with ribosomal proteins via… 
1973
1973
Preparation in vitro of a 2-thiocytidine-containing yeast tRNA Phe -A 73 -C 74 -S 2 C 75 -A 76 and its interaction wiith p-hydroxymercuribenzoate.
2-Thiocytidine (s2C) is incorporated into yeast tRNAphe-A73-C74 by tRNA nucleotidyl transferase. This leads to the formation of… 
1972
1972
Incorporation of 5-iodocytidine into yeast tRNAphe with tRNA nucleotidyl transferase in vitro.
5-Iodocytidine (io5C) is incorporated into tRNAPhe-A73 as well as into tRNAPhe-A73-C74 using tRNA nucleotidyl transferase. The… 
1972
1972
Affinity label for the tRNA binding site on the Escherichia coli ribosome.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)