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perhydrohistrionicotoxin
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Amphibian Venoms
Parasympatholytics
Narrower (1)
H(12)-HTX
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
A gram-scale batch and flow total synthesis of perhydrohistrionicotoxin.
M. Brasholz
,
James M. Macdonald
,
S. Saubern
,
J. H. Ryan
,
A. Holmes
Chemistry
2010
Corpus ID: 3275590
The total synthesis of the spiropiperidine alkaloid (-)-perhydrohistrionicotoxin (perhydro-HTX) 2 has been accomplished on a gram…
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Highly Cited
1993
Highly Cited
1993
Stereocontrolled synthesis via chiral aziridines
D. Tanner
1993
Corpus ID: 98380718
Abstract
1980
1980
Activation, inactivation, and desensitization of acetylcholine receptor channel complex detected by binding of perhydrohistrionicotoxin.
M. Eldefrawi
,
R. Aronstam
,
N. Bakry
,
A. Eldefrawi
,
E. Albuquerque
Proceedings of the National Academy of Sciences…
1980
Corpus ID: 13219507
The effects of receptor activation were studied on the interaction of perhydrohistrionicotoxin (H(12)-HTX) with the ionic channel…
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Highly Cited
1979
Highly Cited
1979
Acetylcholine and local anesthetic binding to Torpedo nicotinic postsynaptic membranes after removal of nonreceptor peptides.
R. Neubig
,
E. Krodel
,
N. Boyd
,
J. Cohen
Proceedings of the National Academy of Sciences…
1979
Corpus ID: 22328585
After alkaline extraction, purified subsynaptic fragments isolated from Torpedo electric tissue exhibit on sodium dodecyl sulfate…
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1979
1979
Binding of perhydrohistrionicotoxin to intact and detergent-solubilized membranes enriched in nicotinic acetylcholine receptor.
J. Elliott
,
M. Raftery
Biochemistry
1979
Corpus ID: 34918340
A tritiated derivative of perhydrohistrionicotoxin was prepared and characterized and used in direct binding studies to membrane…
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1979
1979
Specific binding of perhydrohistrionicotoxin to Torpedo acetylcholine receptor.
J. Elliott
,
S. Dunn
,
S. Blanchard
,
M. Raftery
Proceedings of the National Academy of Sciences…
1979
Corpus ID: 14841949
Torpedo californica postsynaptic membrane fragments were treated with base, which resulted in membranes that were depleted of…
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Highly Cited
1978
Highly Cited
1978
Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations.
M. Eldefrawi
,
A. Eldefrawi
,
N. Mansour
,
J. Daly
,
B. Witkop
,
E. Albuquerque
Biochemistry
1978
Corpus ID: 44868017
The electric organ of the ray, Torpedo ocellata, can serve as a source for both the acetylcholine (ACh) receptor and its ionic…
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Highly Cited
1977
Highly Cited
1977
Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor.
A. Eldefrawi
,
M. Eldefrawi
,
+7 authors
B. Witkop
Proceedings of the National Academy of Sciences…
1977
Corpus ID: 11030567
Histrionicotoxin from the Colombian frog Dendrobates histrionicus and its perhydro derivative reversibly block the acetylcholine…
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1977
1977
A new synthetic route to (+/-)-perhydrohistrionicotoxin.
E. Corey
,
M. Petrzilka
,
Y. Ueda
Helvetica Chimica Acta
1977
Corpus ID: 38417844
Starting from ethyl 2-cyclohexen-1-carboxylate (3) the total synthesis of the perhydrohistrionicotoxin intermediate 23 was…
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Highly Cited
1975
Highly Cited
1975
Effects of histrionicotoxin on the chemosensitive and electrical properties of skeletal muscle
A. Lapa
,
E. Albuquerque
,
J. Sarvey
,
J. Daly
,
B. Witkop
Experimental Neurology
1975
Corpus ID: 29040668
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