Skip to search formSkip to main contentSkip to account menu

penicillin biosynthetic process

Known as: penicillin synthesis, penicillin anabolism, penicillin biosynthesis 
The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system… 
National Institutes of Health

Related topics

Related topics

2 relations
negative regulation of penicillin biosynthetic processpositive regulation of penicillin biosynthetic process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Genes for β-lactam antibiotic biosynthesis
The genespcbAB,pcbC andpenDE encoding enzymes involved in the biosynthesis of penicillin have been cloned fromPenicillium… 
Highly Cited
1989
Highly Cited
1989
delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans. The first enzyme in penicillin biosynthesis is a multifunctional peptide synthetase.
A multienzyme catalyzing the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine, the first free intermediate in… 
Highly Cited
1986
Highly Cited
1986
alpha-Aminoadipate pool concentration and penicillin biosynthesis in strains of Penicillium chrysogenum.
Intracellular amino acid pools in four Penicillium chrysogenum strains, which differed in their ability to produce penicillin… 
1985
1985
Characterization of the biosynthesis in vivo of α-aminoadipyl-cysteinyl-valine inPenicillium chrysogenum
SummaryThe parameters affecting the formation in vivo of α-aminoadipyl-cysteinyl-valine (ACV), an intermediate in penicillin… 
Highly Cited
1984
Highly Cited
1984
A pure enzyme catalyzing penicillin biosynthesis.
Isopenicillin N synthetase (cyclase) has been purified to homogeneity from Cephalosporium acremonium strain C-10. The enzyme has… 
Highly Cited
1979
Highly Cited
1979
Lysine regulation of penicillin biosynthesis in low-producing and industrial strains of Penicillium chrysogenum.
The inhibitory effect of L-lysine on penicillin biosynthesis by Penicillium chrysogenum has been compared in a low-producing… 
1977
1977
Homocitrate synthase as the crucial site of the lysine effect on penicillin biosynthesis.
Homocitrate reverses the lysine inhibition of penicillin bisynthesis. Since lysine is known to inhibit homocitrate synthase… 
Highly Cited
1976
Highly Cited
1976
Synthesis of delta-(alpha-aminoadipyl)cysteinylvaline and its role in penicillin biosynthesis.
1. The stereoisomers of delta-(alpha-aminoadipyl)-L-cysteinylvaline (LLD, LLL and DLD) were synthesized from valine labelled with… 
1960
1960
Influence of valine, isoleucine, and related compounds on actinomycin synthesis.
Highly Cited
1948
Highly Cited
1948
Biosynthesis of penicillins; new crystalline biosynthetic penicillins.
Paper III (1) in this series describes several tests which were found to be useful in determining whether a given compound is… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)