• Publications
  • Influence
The gene structure of human anti‐haemophilic factor IX.
The mRNA sequence of the human intrinsic clotting factor IX (Christmas factor) has been completed and is 2802 residues long, including a 29 residue long 5′ non‐coding and a 1390 residue long 3′Expand
  • 260
  • 5
The sequence of RNA segment 1 of influenza virus A/NT/60/68 and its comparison with the corresponding segment of strains A/PR/8/34 and A/WSN/33.
The complete nucleotide sequence of RNA segment 1 of influenza virus A/NT/60/68, corresponding to the PB2 protein, has been determined. It is 2341 nucleotides long, encoding a predicted product ofExpand
  • 28
  • 3
Cytotoxic T cell recognition of the influenza nucleoprotein and hemagglutinin expressed in transfected mouse L cells
L cells expressing either the A/NT/60/68 nucleoprotein or the A/PR/8/34 (H1) hemagglutinin by DNA mediated gene transfer were used to investigate recognition by influenza A specific cytotoxic TExpand
  • 288
  • 1
The complete sequence of RNA segment 2 of influenza A/NT/60/68 and its encoded P1 protein
A DNA copy of influenza A/NT/60/68 viral RNA segment 2, corresponding to protein P1, has been cloned in the E.coli plasmid pBr322. The clone is 2341 nucleotides long and represents a full-length copyExpand
  • 34
  • 1
Incorporation of 3H from delta-(L-alpha-amino (4,5-3H)adipyl)-L-cysteinyl-D-(4,4-3H)valine into isopenicillin N.
1. delta-(L-alpha-Amino[4,5-3H]adipyl)-L-cysteinyl-D-[4,4-3H]valine has been synthesized from its constituent amino acids, the L-alpha-amino[4,5-3H]adipic acid being obtained by reduction with 3H2 ofExpand
  • 64
  • 1
Conversion of isopenicillin N into penicillin N in cell-free extracts of Cephalosporium acremonium.
In a cell-free system prepared by osmotic lysis of protoplasts of Cephalosporium acremonium, isopenicillin N is converted into penicillin N. The epimerase activity of the system is labile.
  • 46
  • 1
Synthesis of delta-(alpha-aminoadipyl)cysteinylvaline and its role in penicillin biosynthesis.
1. The stereoisomers of delta-(alpha-aminoadipyl)-L-cysteinylvaline (LLD, LLL and DLD) were synthesized from valine labelled with 3H in its methyl groups or in the alpha position.Expand
  • 71
The sequence of the nucleoprotein gene of human influenza A virus, strain A/NT/60/68.
The nucleotide sequence of the nucleoprotein gene of influenza A/NT/60/68 was established after using improved cloning methods to obtain full length cDNA clones in pBr322. The gene is 1565 residuesExpand
  • 110
Influenza A virus evolution: complete sequences of influenza A/NT/60/68 RNA segment 3 and its predicted acidic P polypeptide compared with those of influenza A/PR/8/34.
Abstract The complete sequence of RNA segment 3 of a 1968 isolate of influenza A (A/NT/60/ 68) has been determined from a DNA copy of the viral RNA cloned in the E. coli plasmid pBr322. The segment 3Expand
  • 29
Native American food and medicinal plants, 8. Water-soluble constituents of Lomatium dissectum.
A continuing investigation of the umbellifer Lomatium dissectum has resulted in the isolation of a known flavonoid [1] and three coumarin glycosides [2-4], two of which are previously unreported. OneExpand
  • 28