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pembrolizumab

Known as: Immunoglobulin G4, Anti-(Human Programmed Cell Death 1); Humanized Mouse Monoclonal (228-L-proline(H10-S>P))gamma 4 Heavy Chain (134-218')-disulfide with Humanized Mouse Monoclonal Kappa Light Chain Dimer (226-226'':229-229'')-bisdisulfide, Lambrolizumab 
A humanized monoclonal immunoglobulin (Ig) G4 antibody directed against human cell surface receptor PD-1 (programmed death-1 or programmed cell death… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Immunotherapies have led to substantial changes in cancer treatment and have been a persistently popular topic in cancer research… Expand
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Review
2019
Review
2019
PURPOSE KEYNOTE-158 ( ClinicalTrials.gov identifier: NCT02628067) is a phase II basket study investigating the antitumor activity… Expand
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Review
2019
Review
2019
Monoclonal antibodies targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4), programed cell death 1 (PD-1), or its ligand (PD-L1… Expand
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Review
2019
Review
2019
Background The aim of this meta-analysis was to assess the risks and incidence of nephrotoxicity and electrolyte abnormalities in… Expand
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Review
2019
Review
2019
Following initial successes in melanoma treatment, immunotherapy has rapidly become established as a major treatment modality for… Expand
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Review
2018
Review
2018
BackgroundTherapeutic chances for metastatic melanoma have consistently changed over the last years with the advent of antibodies… Expand
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Highly Cited
2017
Highly Cited
2017
Background Patients with advanced urothelial carcinoma that progresses after platinum‐based chemotherapy have a poor prognosis… Expand
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Highly Cited
2016
Highly Cited
2016
BACKGROUND Despite recent advances in the treatment of advanced non-small-cell lung cancer, there remains a need for effective… Expand
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Highly Cited
2016
Highly Cited
2016
ABSTRACT Introduction: Immune checkpoint inhibitors targeting programmed death protein 1 (PD-1) receptor and its ligand, PD-L1… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND The immune checkpoint inhibitor ipilimumab is the standard-of-care treatment for patients with advanced melanoma… Expand
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