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p21 K-Ras Protein

Known as: p21 c K ras, p21, c-Ki-ras, c-K-ras, p21 
p21 K-RAS protein is encoded by the K-RAS gene. Two KRAS isoforms are produced by alternative splicing. RAS proteins are involved in transmembrane… 
National Institutes of Health

Related topics

Related topics

11 relations
Berzofsky Ras/P53 Peptide VaccineGTP BindingGTP Binding DomainGuanosine Triphosphate Phosphohydrolases

Broader (1)

Proto-Oncogene Proteins p21(ras)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
KRAS-Mutant Lung Cancers in the Era of Targeted Therapy.
KRAS-mutant lung cancers account for approximately 25% of non-small cell lung carcinomas, thus representing an enormous burden of… 
2016
2016
Downregulation of Microrna-126 Contributes to Tumorigenesis of Squamous Tongue Cell Carcinoma via Targeting KRAS
Background miR-126 has been reported to be differentially expressed in various malignancies, whereas its role in the pathogenesis… 
2015
2015
BYL719, a selective inhibitor of phosphoinositide 3-Kinase α, enhances the effect of selumetinib (AZD6244, ARRY-142886) in KRAS-mutant non-small cell lung cancer
SummaryPurposeKRAS is frequently mutated in non-small cell lung cancers (NSCLC), resulting in activation of the MEK/ERK pathway… 
2011
2011
STK33 kinase is not essential in KRAS-dependent cells--letter.
Babij and colleagues report that STK33 is dispensable for KRASmut-dependent cancer cells ([1][1]), a finding in contrast to… 
Highly Cited
2002
Highly Cited
2002
Advantages, Opportunities and Limits of Empirical Evaluations: Evaluating Adaptive Systems
While empirical evaluations are a common research method in some areas of Artificial Intelligence (AI), others still neglect this… 
1999
1999
Stable expression of activated Ki-Ras does not constitutively activate the mitogen-activated protein kinase pathway but attenuates epidermal growth factor receptor activation in human astrocytoma…
Mutation in the ras oncogene is one of the most commonly reported genetic aberrations in human cancer. Activated ras mutants are… 
1996
1996
Influence of GC and AT specific DNA minor groove binding drugs on intermolecular triplex formation in the human c-Ki-ras promoter.
We have used DNase I footprinting and gel shift assays to characterize the interaction of DNA binding drugs mithramycin… 
1994
1994
Different functions of Smg GDP dissociation stimulator and mammalian counterpart of yeast Cdc25.
We have previously shown that both Smg GDP dissociation stimulator (GDS) and mammalian Cdc25 (mCdc25) stimulate the GDP/GTP… 
1987
1987
Enhanced lytic susceptibility of Ha-ras transformants after oncogene induction is specific to activated NK cells.
C3H 10T1/2 mouse fibroblasts were transfected with a plasmid vector composed of EJ, the mutated c-Ha-ras, and a metallothionein… 
1959
1959
Physiologische Untersuchungen an Cerambycidensymbionten
Uber die Symbiose der Cerambyciden besteht eine relativ umfangreiehe Literatur. ttEITZ (1927) beschrieb die Myeetome und die… 
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