Guanosine Triphosphate Phosphohydrolases

Known as: Guanosinetriphosphatase, Triphosphate Phosphohydrolases, Guanosine, GTPases 
Proteins that hydrolyze guanine triphosphate to yield guanine diphosphate. This is a class of proteins that belongs to a family of high energy… (More)

Topic mentions per year

Topic mentions per year

1960-2017
05001000150019602017

Papers overview

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Highly Cited
2010
Highly Cited
2010
  • 2010
The autism spectrum disorders (ASDs) are a group of conditions characterized by impairments in reciprocal social interaction and… (More)
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Highly Cited
2010
Highly Cited
2010
The mTORC1 kinase promotes growth in response to growth factors, energy levels, and amino acids, and its activity is often… (More)
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Highly Cited
2008
Highly Cited
2008
The multiprotein mTORC1 protein kinase complex is the central component of a pathway that promotes growth in response to insulin… (More)
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Highly Cited
2006
Highly Cited
2006
Dynamin is essential for clathrin-dependent coated vesicle formation. It is required for membrane budding at a late stage during… (More)
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Highly Cited
2004
Highly Cited
2004
The target of rapamycin (TOR) is a highly conserved protein kinase and a central controller of cell growth. In budding yeast, TOR… (More)
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Highly Cited
2003
Highly Cited
2003
Tuberous sclerosis complex (TSC) is a genetic disease caused by mutation in either TSC1 or TSC2. The TSC1 and TSC2 gene products… (More)
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Highly Cited
1997
Highly Cited
1997
Abnormal smooth-muscle contractility may be a major cause of disease states such as hypertension, and a smooth-muscle relaxant… (More)
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Highly Cited
1996
Highly Cited
1996
The small GTPase Rho is implicated in physiological functions associated with actin-myosin filaments such as cytokinesis, cell… (More)
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Highly Cited
1995
Highly Cited
1995
Rho and rac, two members of the ras-related superfamily of small GTPases, regulate the polymerization of actin to produce stress… (More)
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Highly Cited
1994
Highly Cited
1994
Vascular endothelial growth factor (VEGF) is a homodimeric peptide growth factor which binds to two structurally related tyrosine… (More)
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