Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Acid Anhydride Hydrolases

Known as: Acid Anhydride Hydrolases [Chemical/Ingredient], acid anhydride hydrolase, Anhydride Hydrolases, Acid 
A group of enzymes that catalyze the hydrolysis of diphosphate bonds in compounds such as nucleoside di- and tri-phosphates, and sulfonyl-containing… Expand
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (26)

Actomyosin AdenosinetriphosphataseAcylphosphataseAdenosine TriphosphatasesCEL-1 protein, C elegans
Expand

Broader (1)

Hydrolase
In BloodPhosphoric Monoester HydrolasesProcess of secretionantagonists & inhibitors
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Development of organophosphate hydrolase activity in a bacterial homolog of human cholinesterase
We applied a combination of rational design and directed evolution (DE) to Bacillus subtilis p-nitrobenzyl esterase (pNBE) with… Expand
  • figure 1
  • figure 2
  • table 1
  • table 2
  • table 3
Highly Cited
2010
Highly Cited
2010
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents
The concept of using cholinesterase bioscavengers for prophylaxis against organophosphorous nerve agents and pesticides has… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
2000
2000
Expression of biologically active human butyrylcholinesterase in the cabbage looper (Trichoplusia ni)
This investigation examined the utility of three recombinant protein‐expression systems (COS cells, insect cells and insect… Expand
Highly Cited
1998
Highly Cited
1998
Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase.
Organophosphorus acid anhydride (OP) "nerve agents" are rapid, stoichiometric, and essentially irreversible inhibitors of serine… Expand
Highly Cited
1997
Highly Cited
1997
A single amino acid substitution, Gly117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase.
The G117H mutant of human butyrylcholinesterase (EC 3.1.1.8) was expressed in Chinese hamster ovary cells. Substitution of Gly… Expand
Highly Cited
1995
Highly Cited
1995
Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase.
Serine esterases and proteases are rapidly and irreversibly inhibited by organophosphorus (OP) nerve agents. To overcome this… Expand
1993
1993
A purified recombinant organophosphorus acid anhydrase protects mice against soman.
  • C. Broomfield
  • Chemico-biological interactions
  • 1993
    • Corpus ID: 30939232
Since pharmacologic treatments of organophosphorus anticholinesterases (OPs) are nearing their practical limit other types of… Expand
1992
1992
A purified recombinant organophosphorus acid anhydrase protects mice against soman.
Since pharmacologic treatments of organophosphorus anticholinesterases (OPs) are nearing their practical limit other types of… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE