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Acid Anhydride Hydrolases

Known as: Acid Anhydride Hydrolases [Chemical/Ingredient], acid anhydride hydrolase, Anhydride Hydrolases, Acid 
A group of enzymes that catalyze the hydrolysis of diphosphate bonds in compounds such as nucleoside di- and tri-phosphates, and sulfonyl-containing… Expand
National Institutes of Health

Papers overview

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2014
2014
We applied a combination of rational design and directed evolution (DE) to Bacillus subtilis p-nitrobenzyl esterase (pNBE) with… Expand
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Highly Cited
2010
Highly Cited
2010
The concept of using cholinesterase bioscavengers for prophylaxis against organophosphorous nerve agents and pesticides has… Expand
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2000
2000
This investigation examined the utility of three recombinant protein‐expression systems (COS cells, insect cells and insect… Expand
Highly Cited
1998
Highly Cited
1998
Organophosphorus acid anhydride (OP) "nerve agents" are rapid, stoichiometric, and essentially irreversible inhibitors of serine… Expand
Highly Cited
1997
Highly Cited
1997
The G117H mutant of human butyrylcholinesterase (EC 3.1.1.8) was expressed in Chinese hamster ovary cells. Substitution of Gly… Expand
Highly Cited
1995
Highly Cited
1995
Serine esterases and proteases are rapidly and irreversibly inhibited by organophosphorus (OP) nerve agents. To overcome this… Expand
1993
1993
  • C. Broomfield
  • Chemico-biological interactions
  • 1993
  • Corpus ID: 30939232
Since pharmacologic treatments of organophosphorus anticholinesterases (OPs) are nearing their practical limit other types of… Expand
1992
1992
Since pharmacologic treatments of organophosphorus anticholinesterases (OPs) are nearing their practical limit other types of… Expand