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p120 GTPase Activating Protein

Known as: GAP, p120, p120-GAP Protein, p120 GTPase Activating Protein [Chemical/Ingredient] 
A 120-kDa RAS GTPase-activating protein that binds to tyrosine phosphoproteins through its SH2 domains. The 100-kDa RNA-splicing variant (p100 GAP… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

GTPase-Activating Proteins
In BloodProcess of secretionRASA1 geneRASA1 wt Allele

Narrower (1)

p100-GAP Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide
The Rho and Ras pathways play vital roles in cell growth, division and motility. Cross-talk between the pathways amplifies their… 
2014
2014
p120RasGAP Is a Mediator of Rho Pathway Activation and Tumorigenicity in the DLD1 Colorectal Cancer Cell Line
KRAS is mutated in ∼40% of colorectal cancer (CRC), and there are limited effective treatments for advanced KRAS mutant CRC… 
2012
2012
Tumor and Stem Cell Biology p 120 RasGAP-Mediated Activation of cSrc Is Critical for Oncogenic Ras to Induce Tumor Invasion
Ras genes are the most common targets for somatic gain-of-function mutations in human cancers. In this study, we found a high… 
2010
2010
Bifunctional role of the zinc finger domains of the methyl-DNA-binding protein Kaiso
DNA methylation is common for all vertebrates and is one of the major epigenetic marks associated with a transcriptionally… 
2010
2010
[Bifunctional role of domain zinc fingers of methyl-DNA-binding protein Kaiso].
DNA methylation in mammals is one of the major epigenetic mark that associates with inactive chromatin state. Methyl-DNA-binding… 
Highly Cited
2006
Highly Cited
2006
Eph receptors inactivate R-Ras through different mechanisms to achieve cell repulsion
Eph receptor tyrosine kinases regulate the spatial organization of cells within tissues. Central to this function is their… 
2005
2005
P125 - Carcinome annexiel microkystique : 6 cas
2004
2004
Author index
A&h u&t, E.G.J. : 13 Alcaraz, M. : 14 Alexander, E. : 69 Alexander, V. : 15 Alfaro, R.T. : 1031 Ali, M.A. : 540 Allan, J.D. : 16… 
2001
2001
Identification of p 125 , a Component of a Group of 120-kDa Proteins That Are Phosphorylated on Tyrosine Residues in Response to Bradykinin and Bombesin Stimulation , in Anti-Ras-GTPase-activating…
Bradykinin (BK) and bombesin (BN) stimulate an increase in the tyrosine phosphorylation of a 120-kDa group of proteins (ppsl20… 
1998
1998
Sequence and 3D structural relationships between mammalian Ras‐ and Rho‐specific GTPase‐activating proteins (GAPs): the cradle fold
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