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ortataxel

Known as: SB-T-101131 
A semisynthetic, second-generation taxane derivative with potential antineoplastic activity. Ortataxel binds to and stabilizes tubulin molecules… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

IDN 5109
Microtubule ProcessNCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Targeted Delivery of Nanoparticle Based Taxanes for Breast Cancer Treatment: A Review
The most common type of cancers in women is breast cancer. In United States, it is the second common cause of death in women… 
2014
2014
The synthesis of novel taxoids for oral administration.
2008
2008
Phase II study of ortataxel in taxane-resistant breast cancer
1066 Background: Ortataxel, a new-generation taxane, is not a substrate for the Pgp efflux pump. It is active in tumor models… 
2008
2008
Gateways to clinical trials.
Gateways to clinical trials is a guide to the most recent trials in current literature and congresses. The data in the following… 
Review
2005
Review
2005
Recent advances in the new generation taxane anticancer agents.
Recent advances in the design and preclinical evaluations of promising new generation taxane anticancer agents are reviewed in… 
Review
2004
Review
2004
An uncontrolled phase II study evaluating anti-tumor efficacy and safety of ortataxel (BAY 59-8862) in patients with taxane-resistant non-small cell lung cancer.
7136 Background: Ortataxel is a novel second-generation taxane, with potent growth inhibitory activity against human cell lines… 
2004
2004
Gateways to clinical trials.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
2004
2004
Gateways to clinical trials.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
Review
2004
Review
2004
Gateways to clinical trials.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
2003
2003
Diastereoselective 14beta-hydroxylation of baccatin III derivatives.
14beta-Hydroxybaccatin III, a compound with limited availability by natural sources, is the starting material for the synthesis… 
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